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Xylazine CAS NO: 7361-61-7 Rompun, Anased, Sedazine, Chanazine

incazelo emfushane:


  • INOMBOLO YECAS ::7361-61-7
  • Igama::I-Xylazine
  • Ifomula yemolekyuli::C 12 H 16 N 2 S
  • I-Molar mass::220.33
  • Iphoyinti lokuncibilika:140ºC
  • Indawo yokubilisa:334.2±52.0 °C ku-760 mmHg
  • ukuminyana:1.2±0.1 g/cm3
  • I-imeyili:: salesexecutive1@yeah.net
  • ungitshele::lilywang
  • Wahtsapp::+8618931626169
  • Imininingwane Yomkhiqizo

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    Thinta mina

    Email : salesexecutive1@yeah.net

    whatsapp: +8618931626169

    wickr: lilywang

    Ukusetshenziswa

    Ukusetshenziswa kwezokwelapha
    I-Toluene thiazide ivame ukusetshenziswa njenge-sedative, i-muscle ephumuzayo kanye ne-analgesic.Ngokuvamile isetshenziselwa ukwelapha i-tetanus.I-Xylazine ifana kakhulu nezidakamizwa ezifana ne-phenothiazine, i-tricyclic antidepressants ne-clonidine.Njenge-anesthetic, ivame ukusetshenziswa ngokuhambisana ne-ketamine.I-Xylazine ibonakala inciphisa ukuzwela komzimba ku-insulin nokuthathwa kwe-glucose.I-Yohimbine iyi-alpha2 adrenergic receptor antagonist esetshenziselwe ukwehlisa amazinga eglucose kumazinga anempilo.I-Yohimbine ibuyisela emuva imiphumela emibi ye-toluene thiazide esimweni somtholampilo uma ilawulwa ngomthambo ngokushesha ngemva kokuphathwa kwe-toluene thiazide.

    i-pharmacodynamics

    I-Xylazine iyi-agonist enamandla ye-alpha 2 adrenergic.I-Toluene thiazide namanye ama-agonists e-alpha2 adrenergic receptor asatshalaliswa emzimbeni wonke phakathi nemizuzu engama-30-40 lapho enikezwe.Ngenxa ye-lipophilicity yayo ephezulu, i-toluene thiazide ivuselela ngokuqondile ama-receptors aphakathi kwe-α2 kanye nama-receptor e-alphaadrenergic ezinhlobonhlobo zezicubu.Njenge-agonist, i-toluene thiazide iphumela ekunciphiseni kwe-neurotransmission ye-norepinephrine ne-dopamine ohlelweni lwezinzwa olumaphakathi.Lokhu ikwenza ngokulingisa ukuboshwa kwe-norepinephrine kuma-autoreceptors endaweni ye-presynaptic, okuholela ekuvinjweni kwempendulo ye-norepinephrine.

    I-Xylazine iphinde isebenze njenge-inhibitor yokuthutha ngokuvimbela umsebenzi wokuthutha we-norepinephrine ngokuncintisana ngokuvimbela ukuthutha kwe-substrate.Ngakho-ke, i-toluene thiazide yenyusa kakhulu i-K m futhi ayizange ithinte i-V max.Lokhu kungenzeka ngokusebenzisana okuqondile nezifunda ezigqagqene nezindawo ezibopha i-antidepressant.Isibonelo, i-toluene thiazide ne-clonidine ivimbela ukutholwa kwe-MIBG (i-norepinephrine analogue) ngamaseli e-neuroblastoma.I-Xylazine inama-affinities ahlukene e-cholinergic, i-serotonergic, i-dopaminergic, i-alpha1, i-adrenergic, i-H 2-histamine, ne-opioid receptors.Isakhiwo sayo samakhemikhali sifana kakhulu nesama-phenothiazines, ama-tricyclic antidepressants kanye ne-clonidine

     

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