I-Trenbolone Cyclohexylmethylcarbonate CAS:23454-33-3 11-trien-3-one carbonate cyclohexylMethylcarbonate (8CI)

Isingeniso esifushane:
Trenbolone (TRE) is a steroid protein assimilation hormone esetshenziswa kabanzi.Kuyi-chemosynthetic derivative efana ne-testosterone yehomoni yomuntu wesilisa ngesakhiwo nomsebenzi.Ingakhuthaza ukwakheka kwamaprotheni, yandise isifiso sokudla, yandise imisipha, ikhuthaze i-calcium ne-phosphorus esicutshini samathambo, futhi ingasetshenziswa emtholampilo ukwelapha ukuntula okunamandla komsoco kanye ne-osteoporosis, kodwa futhi iwuhlobo oluvame ukusetshenziswa kakhulu lwesikhuthazi sezemidlalo.Iqembu le-bolone cyclohexyl methyl carbonate lingasetshenziswa njengendawo yokwenziwa yeqembu leBolone.
Ukulungiselela:
Iqembu le-bromcyclohexyl methyl carbonate lilungiswa kanje:
I-3G17/3-hydroxy-estradiol-4,9, 11-triene-3-one incibilike ku-pyridine ngo-15℃ kanye no-0℃ ngaphansi kokuyaluza nomoya we-nitrogen.Gcina izinga lokushisa liphakathi kuka-0 no-10 degrees Celsius.Faka kancane kancane i-50ml i-hexahydrobenzyl chloride Chemicalbook formate, bese ufudumeza yonke ingxube ekushiseni okuzungezile, ugovuze amahora amabili, bese upholisa ku-0 ° C. Faka i-triethylamine bese ugoqa imizuzu engu-30 ukuze ukhuphule izinga lokushisa endaweni bese uthela ingxube yokusabela ingxube yamanzi/iqhwa.Yakhishwa nge-methylene chloride, futhi isigaba se-organic sagezwa ngamanzi ukuze singathathi hlangothi, somiswe nge-sodium sulfate, futhi sihwamuke ngaphansi kwe-vacuum kuze kube somile.Izinsalela zahlukaniswa nge-chromatography kujeli ye-silica, yakhishwa ngengxube engu-4:1 ye-benzene/ethyl acetate, yaphinde yahlanganiswa nengxube ye-isopropyl ether/hexane.I-Chromatography yenziwe futhi kujeli ye-silica, yakhishwa ngengxube ye-benzene/ethyl acetate, futhi ekugcineni yafakwa kabusha ku-cyclohexane ne-petroleum ether ukuze kutholwe i-1.60g yeqembu le-bromcyclohexyl methyl carbonate.Umkhiqizo ubonakala njenge-prism encibilikayo ku-ethanol, ether, benzene, acetone, ne-chloroform, kodwa ongancibiliki emanzini, e-dilute acid, nezixazululo ze-lye.