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imikhiqizo

Imithi elwa nesithuthwane Umuthi Ibanga le-Pharma Ithebulethi Yempushana eshisayo emaphakathi CAS 148553-50-8

incazelo emfushane:


  • Iphoyinti lokuncibilika:194-196 ° C
  • Ngokukhanya kwe-Rotor:I-D23+10.52 ° (C = 1.06emanzini)
  • Indawo yokubilisa:274.0 ± 23.0 ° C (Predict)
  • Ukuminyana :0.997 ± 0.06g/cm3 (PredcheMicalbookicted)
  • Iphoyinti le-Flash:9°C
  • izimo zokugcina:2-8 ° C
  • Ukunyibilika :amanzi deionized: ≥10mg/mL
  • Ifomu:impushana emhlophe
  • I-Pka:4.23±0.10(Okubikezelwe)
  • Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

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                                                   Ukusetshenziswa kwe-CAS 148553-50-8:

    I-CAS 148553-50-8 iyi-analog ye-neurotransmitter gamma-aminobutyric acid (GABA), ethengiswa ngaphansi kwegama lokuhweba.NgoZibandlela wezi-2004, i-FDA yagunyaza i-CAS 148553-50-8 njengomuthi wokwelapha i-neuralgia yesifo sikashukela kanye ne-herpes zoster neuralgia.I-CAS 148553-50-8 umuthi wokuqala owagunyazwa yi-United States naseYurophu ukuze uphathe ngenhla kwezinhlobo ezimbili zobuhlungu.NgoJuni 2005, i-CAS 148553-50-8 yagunyazwa ukwelashwa kwe-adjuvant yesithuthwane esiyingxenye yabantu abadala.NgoMashi 2006, i-European Union yagunyaza i-CAS 148553-50-8 yokwelashwa kwe-generalized Anxiety Disorder (GAD) kanye ne-Social Anxiety Disorder (SAD).
                  
    I-CAS 148553-50-8 isetshenziselwa ikakhulukazi ukwelashwa kwe-peripheral neuralgia kanye nokwelashwa kwe-adjuvant kokuquleka okuyingxenye kwendawo.
    I-CAS 148553-50-8 ingase yehlise ukukhululwa okuncike ku-calcium kwamanye ama-neurotransmitters ngokumodela ukusebenza kwesiteshi se-calcium.Nakuba i-CAS 148553-50-8 iwukuphuma kwesakhiwo se-neurotransmitter engavimbeli i-γ-aminobutyric acid (GABA), ayibophezeli ngokuqondile ku-GABAA, GABAB, noma kuma-benzodiazepine receptors futhi ayinyusi i-GABAA ku-Culated neurons Response, ayizange ishintshe ukuhlushwa kwe-GABA ebuchosheni bamagundane, futhi akuzange kube nomthelela omkhulu ekuthathweni noma ekucekeleni phansi kwe-GABA.Kodwa-ke, ucwaningo lwathola ukuthi ukuchayeka isikhathi eside kwama-neurons akhulisiwe ku-CAS 148553-50-8 kukhulisa ukuminyana kwabathuthi be-GABA kanye nezinga lokuhamba kwe-GABA okusebenzayo.I-CAS 148553-50-8 ayivimbi iziteshi zesodium, ayinawo umsebenzi kuma-opioid receptors, ayishintshi umsebenzi we-cyclooxygenase, ayinawo umsebenzi ku-dopamine ne-serotonin receptors, futhi ayivimbeli ukuvuselelwa kwe-dopamine, i-serotonin, ukungena.

    148553-50-8

    CAS 148553-50-8 omqondofana:

    3(Izi-)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID

    (3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID

    3-(Aminomethyl) -5-methyl-hexanoic acid

    I-PREDNISOLONESODIUMPHOSPHATE

     

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