Imithi elwa nesithuthwane Umuthi Ibanga le-Pharma Ithebulethi Yempushana eshisayo emaphakathi CAS 148553-50-8
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Ukusetshenziswa kwe-CAS 148553-50-8:
I-CAS 148553-50-8 iyi-analog ye-neurotransmitter gamma-aminobutyric acid (GABA), ethengiswa ngaphansi kwegama lokuhweba.NgoZibandlela wezi-2004, i-FDA yagunyaza i-CAS 148553-50-8 njengomuthi wokwelapha i-neuralgia yesifo sikashukela kanye ne-herpes zoster neuralgia.I-CAS 148553-50-8 umuthi wokuqala owagunyazwa yi-United States naseYurophu ukuze uphathe ngenhla kwezinhlobo ezimbili zobuhlungu.NgoJuni 2005, i-CAS 148553-50-8 yagunyazwa ukwelashwa kwe-adjuvant yesithuthwane esiyingxenye yabantu abadala.NgoMashi 2006, i-European Union yagunyaza i-CAS 148553-50-8 yokwelashwa kwe-generalized Anxiety Disorder (GAD) kanye ne-Social Anxiety Disorder (SAD).
I-CAS 148553-50-8 isetshenziselwa ikakhulukazi ukwelashwa kwe-peripheral neuralgia kanye nokwelashwa kwe-adjuvant kokuquleka okuyingxenye kwendawo.
I-CAS 148553-50-8 ingase yehlise ukukhululwa okuncike ku-calcium kwamanye ama-neurotransmitters ngokumodela ukusebenza kwesiteshi se-calcium.Nakuba i-CAS 148553-50-8 iwukuphuma kwesakhiwo se-neurotransmitter engavimbeli i-γ-aminobutyric acid (GABA), ayibophezeli ngokuqondile ku-GABAA, GABAB, noma kuma-benzodiazepine receptors futhi ayinyusi i-GABAA ku-Culated neurons Response, ayizange ishintshe ukuhlushwa kwe-GABA ebuchosheni bamagundane, futhi akuzange kube nomthelela omkhulu ekuthathweni noma ekucekeleni phansi kwe-GABA.Kodwa-ke, ucwaningo lwathola ukuthi ukuchayeka isikhathi eside kwama-neurons akhulisiwe ku-CAS 148553-50-8 kukhulisa ukuminyana kwabathuthi be-GABA kanye nezinga lokuhamba kwe-GABA okusebenzayo.I-CAS 148553-50-8 ayivimbi iziteshi zesodium, ayinawo umsebenzi kuma-opioid receptors, ayishintshi umsebenzi we-cyclooxygenase, ayinawo umsebenzi ku-dopamine ne-serotonin receptors, futhi ayivimbeli ukuvuselelwa kwe-dopamine, i-serotonin, ukungena.
CAS 148553-50-8 omqondofana:
3(Izi-)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
3-(Aminomethyl) -5-methyl-hexanoic acid
I-PREDNISOLONESODIUMPHOSPHATE
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