Oral Injectable Anabolic Steroid L-Triiodothyronine T3 Anabolic Steroids Powder CasNO.55-06-1
I-T3(Liothytonine Sodium) Imininingwane Esheshayo
- I-L-Triiodothyronine(T3)
- Isibizo:3,3',5-Triiodo-L-thyroninesodiumsalt,Sodium(2S)-2-amino-3--[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
- Ubumsulwa: 99%
- Inombolo yokubhalisa ye-CAS: 55-06-1
- Inombolo ye-Einecs: 200-223-5
- MF: C15H11I3NNaO4
- MW: 672.96
- Ukubukeka: impushana emhlophe noma ekhanyayo ephuzi, cishe ayinambitheki.
- Ibanga: Ibanga Lezemithi
- Isitoreji: Ukufiphaza, ukulondolozwa okuvalekile
- Ukusetshenziswa : Kuthinta cishe yonke inqubo yomzimba emzimbeni, okuhlanganisa ukukhula nokuthuthuka, i-metabolism, izinga lokushisa lomzimba, nokushaya kwenhliziyo, njengokwelashwa kwezinkinga zokucindezeleka nokusetshenziswa njengesithasiselo sokulahlekelwa kwamafutha.
- I-T3(Liothytonine Sodium)Isicelo
- Ithinta cishe yonke inqubo yomzimba emzimbeni, okuhlanganisa ukukhula nokuthuthuka, i-metabolism, izinga lokushisa lomzimba, nokushaya kwenhliziyo.I-T3 inyusa izinga lokusatshalaliswa kwe-basal futhi, ngaleyo ndlela, yandisa umoya-mpilo womzimba nokusetshenziswa kwamandla.Izinga le-basal metabolic liyisidingo esincane sekhalori esidingekayo ukuze kuqhubeke ukuphila komuntu ophumule.I-T3 isebenza kuzicubu eziningi emzimbeni, ngaphandle kokumbalwa okuhlanganisa ubende namasende.Yandisa ukukhiqizwa kwe-Na+/K+ -ATPase futhi, ngokuvamile, yandisa inzuzo yama-macromolecules ahlukene e-endogenous ngokwandisa ukuhlanganiswa kwawo nokuwohloka.
T3(Liothytonine Sodium) Incazelo
I-Triiodothyronine, eyaziwa nangokuthi i-T3, i-hormone yegilo.Kuthinta cishe yonke inqubo yomzimba emzimbeni, okuhlanganisa ukukhula nokukhula, i-metabolism, izinga lokushisa lomzimba, nokushaya kwenhliziyo.
Ukukhiqizwa kwe-T3 kanye ne-prohormone thyroxine (T4) kwenziwa kusebenze i-hormone ye-thyroid-stimulating (TSH), ekhishwa ku-pituitary gland.Le ndlela ilawulwa ngenqubo yempendulo evaliwe: Ukugxila okuphezulu kwe-T3, ne-T4 ku-plasma yegazi kuvimbela ukukhiqizwa kwe-TSH ku-pituitary gland.Njengoba ukugxila kwala mahomoni kuncipha, indlala ye-pituitary ikhulisa ukukhiqizwa kwe-TSH, futhi ngalezi zinqubo, kumiswa uhlelo lokulawula impendulo ukuze lilawule inani lamahomoni egilo asegazini.
Njenge-hormone yeqiniso, imiphumela ye-T3 ezicutshini ezihlosiwe inamandla aphindwe kane kunalawo e-T4.Ku-hormone yegilo ekhiqizwayo, cishe i-20% yi-T3, kuyilapho i-80% ikhiqizwa njenge-T4.Cishe u-85% we-T3 ejikelezayo kamuva yakheka ku-thyroid ngokukhipha i-athomu ye-iodine kunombolo ye-carbon athomu yesihlanu yeringi yangaphandle ye-T4.Kunoma yikuphi, ukugcwala kwe-T3 ku-plasma yegazi lomuntu cishe kuyingxenye yamashumi amane kune-T4.Lokhu kubonakala eqinisweni ngenxa yesigamu sokuphila esifushane se-T3, okuyizinsuku ezingu-2.5 kuphela.Lokhu kuqhathaniswa nesigamu sempilo ye-T4, okuyizinsuku ezingaba ngu-6.5.
I-COA:
| Into | Ukucaciswa | Umphumela | |
| Ukubukeka | Impushana enombala engenaphunga, cishe emhlophe noma e-buff | dlula | |
| Ukuncibilika | 1,Incibilika kancane emanzini | dlula | |
| 2,incibilika kancane otshwaleni | dlula | ||
| 3, ayincibiliki kwezinye izinyibilikisi eziningi eziphilayo | dlula | ||
| 4, incibilika kuzixazululo ze-sodium hydroxide exutshiwe | Dlula | ||
| Ukuhlonza | a) Shisisa cishe u-50 mg ngamaconsi ambalwa e-sulfuric acid ku-porcelain crucible: i-violet vapor ye-iodine iyavela. | dlula | |
| b)Isikhathi sokugcina sesiqongo esikhulu siqinisekiswa ku-RS | dlula | ||
| Ukulahlekelwa Ekumisweni | Hhayi ngaphezu kuka-4.0% | 0.46% | |
| [a]20/D C=1 ku-1M HCl/EtOH 1:4 | +18 ~ +22o | ＋20.9o | |
| I-Assay(HPLC) | Hhayi ngaphansi kuka-95.0% | 99.18% | |
| Levothyroxine sodium | Hhayi ngaphezu kuka-5.0% | 0.68% | |
| Isiphetho: | Kufike Kuzinga Lokuthekelisa | ||
Ukupakisha Nokulethwa
