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Ukunikezwa kokukhiqiza Dihexa CAS 1401708-83-5

incazelo emfushane:


  • Iphoyinti lokuncibilika:Iphoyinti lokuncibilika
  • Indawo yokubilisa:866.2 ± 65.0 ° C (Predict)
  • Ukuminyana:1.111 ± 0.06g/cm3 (Predict) (Predict)
  • 1.111 ± 0.06g/cm3 (Predict) (Predict):Hygroscopic, Isiqandisi, UnderinchemicalBooKertatmosphere
  • Ukunyibilika:I-DMSO (Kancane), i-Methanol (Kancane)
  • Ifomu:okuqinile
  • (I-PKA):9.83 ± 0.15 (Ukubikezela)
  • I-imeyili: ceo66@hbainuodi.com
  • Whatsapp:+8618849057872
  • Wickr:ali868
  • Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Thinta mina:

    Email:ceo66@hbainuodi.com

    Whatsapp:+8618849057872

    Wickr: alice868

    图片2
    I-Dihexa CAS 1401708-83-5

    Ukusetshenziswa:

    I-DIHEXA (PNB-0408), i-oligoplase reagent, iyi-analog ye-IV ye-vascular tensionin IV enomsebenzi womlomo kanye nokungena kwe-blood-brain barrier.I-Dihexa enobungane kakhulu namandla ihlanganisa i-hepatocyte growth factor (HGF), inani le-ChemicalBookkd lingu-65PM, futhi ithuthukisa umsebenzi wayo kumamukeli we-C-MET.I-Dihexa ibonisa umsebenzi omuhle kakhulu we-anti -ejaculation futhi ithuthukise imisebenzi yengqondo kumamodeli ezilwane.I-Dihexa inamandla okutadisha isifo i-Alzheimer's.

    I-Dihexa ibophezela ngokuhambisana okuphezulu ku-HGF futhi kokubili i-dihexa kanye nenhlanganisela yomzali wayo i-Norleucine 1-AngIV yenza i-c-Met phosphorylation phambi kokugxila kwe-subthreshold ye-HGF futhi ikhulise ukusabalalisa kwamaseli okuncike ku-HGF.Ngaphezu kwalokho, i-dihexa ne-Nle1-AngIV yenza i-hippocampal spinogenesis kanye ne-synaptogenesis efana ne-HGF ngokwayo.I-Dihexa ivimbela ngempumelelo i-HGF dimerization ku-1 μM. Ngenkathi i-dihexa ku-1 nM kanye no-10 pM iyodwa ingayisebenzisi i-c-Met, ikhulisa ngokuphawulekayo umthamo we-HGF ku-1.25 kanye no-2.5 ​​ng/mL ukuze iqalise i-c-Met.

    I-Dihexa ine-half-life ejikelezayo ende.I-Dihexa ibonisa umsebenzi wokuqonda.I-Dihexa ihlehlisa ukushoda kokufunda kwendawo okuncike ku-scopolamine.Ithuthukisa ukufunda kwendawo kumagundane asebekhulile.I-Dihexa yenza i-spinogenesis kuma-neuron e-hippocampal akhulisiwe.

    Uma unezinkinga, ungaxhumana nathi ngokukhululekile.

    Uma uxhumene nomkhiqizo wamakhemikhali, sicela usithinte.Singakhuluma kabanzi.Singakunikeza imininingwane yomkhiqizo eyengeziwe.


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