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imikhiqizo

I-GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide

incazelo emfushane:


  • INOMBOLO YE-CAS:170851-70-4
  • Igama:I-GHRP-2/Pralmorelin
  • Ifomula yekhemikhali:C 45 H 55 N 9 O 6
  • Iphoyinti lokuncibilika :149 - 151°C
  • Izinga lokushisa lokulondoloza:−20°C
  • pka:13.40±0.46(Okubikezelwe)
  • Indawo yokubilisa:1265.3±65.0 °C(Kubikezelwe)
  • ifomu:impushana
  • I-Molar mass:817.992
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  • Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Ukusetshenziswa

    I-Pralmorelin (INN) (igama lokuhweba i-GHRP Kaken 100; Amagama ekhodi yokuthuthukiswa yangaphambilini KP-102, GPA-748, WAY-GPA-748), eyaziwa nangokuthi i-pralmorelin hydrochloride (JAN) ne-pralmorelin dihydrochloride (USAN), futhi ikakhulukazi, Ukukhula i-hormone ekhulula i-Peptide 2 (GHRP-2), i-hormone yokukhula i-secretagotor (GHS), isetshenziswa njenge-ejenti yokuxilonga futhi idayiswa ngefomu lokwenziwa kwedosi elilodwa yi-Kaken Pharmaceutical yaseJapane ukuze kuhlolwe ukuntuleka kwe-hormone yokukhula (GHD).

    I-Pralmorelin iyisidakamizwa se-peptide sokwenziwa esinomsebenzi womlomo.Ngokuqondile, i-analogue ye-methoxyenkephalin ene-amino acid ukulandelana kwe-D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Isebenza njenge-auxin ekhulula i-peptide / i-hormone yokukhula i-secretin receptor ( GHSR) i-agonist futhi umuthi wokuqala wohlobo lwayo owethulwa emtholampilo.Ukuphathwa okunamandla komuthi kukhulisa kakhulu amazinga e-plasma growth hormone (GH) futhi kubangele indlala ngokuthembekile futhi kwandisa ukudla kwabantu.

    I-Pralmorelin nayo ifundelwa i-GHD kanye nesiqu esifushane (pituitary dwarfism) futhi yangena ezivivinyweni zomtholampilo zesigaba II ngalezi zinkomba, kodwa ekugcineni ayizange ikwazi ukumaketha.Lokhu kungenzeka kungenxa yokuthi amandla e-pramoline okwandisa amazinga e-GH e-plasma aphansi kakhulu ezigulini ze-GHD kunabantu abanempilo.

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