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I-Chemical Material Izidakamizwa ezisizayo Izidakamizwa ezisizayo CAS 59-46-1 PROCAINE

incazelo emfushane:


  • Igama elijwayelekile:PROCAINE
  • Inombolo ye-CAS:59-46-1
  • MF:I-C13H20N2O2
  • MW:236.31
  • I-EINECS:200-426-9
  • Iphoyinti lokuncibilika:61°
  • Indawo yokubilisa:378.78°C (isilinganiso esinzima)
  • ukuminyana :1.0604 (isilinganiso esinzima)
  • Izinga lokushisa lokulondoloza:Gcina endaweni emnyama, evalwe endaweni eyomile, Emazingeni Okushisa Egumbi
  • inkomba ye-refractive:1.5430 (isilinganiso)
  • ukuncibilika :I-DMSO (Kancane), i-Methanol (Kancane)
  • pka:9.04±0.01(H2O,t=25,I=0.1(NaCl))(Cishe)
  • ifomu:Okuqinile
  • umbala:okumhlophe kuya kokumhlophe
  • Iphakheji:Isikhwama, Ikhathoni
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    Ulwazi Oluyisisekelo

    59-46-1

    Incazelo

    I-Procaine iyisibulala-zinzwa sasendaweni esinomsebenzi we-para-amino.Ukuzwela kuthinta ikakhulukazi umsebenzi wezokwelapha, wamazinyo nowezilwane.

    Chemical Properties

    Usawoti we-hydrochloride we-2-(diethylamino) ethyl p-aminobenzoate (C13H21ClN2O2 noma i-N2C6H4COOCH2CH2NH(C2H5)2HCl) ngokuvamile ubizwa ngokuthi i-procaine.Nakuba i-PABA ester ingancibiliki emanzini, usawoti we-hydrochloride uncibilika kakhulu emanzini.

    Isebenzisa

    I-1.I-Procaine (i-Novocain) isetshenziselwa ikakhulukazi izinqubo zamazinyo noma zezokwelapha ezidinga i-anesthesia yokungena, i-peripheral block, noma i-spinal block.

    I-2.inhibitor yesiteshi se-sodium

    3. I-Procaine iyisivimbeli sesiteshi se-sodium kanye ne-inhibitor yezinqubo ezihlukahlukene.

    I-CAS 94-15-5
    Levamisole
    Levamisole

    Ukusetshenziswa

    Ukusetshenziswa KwezokwelaphaI-procaine igaywa ngokushesha ku-plasma ngama-cholinesterase nasesibindini nge-ester hydrolysis nge-pseudocholinesterase.I-in vitroelimination half-life cishe imizuzwana engama-60.Noma yisiphi isimo esinciphisa ukugxila kwe-cholinesterase singase sikhulise ukuchayeka ku-procaine kanye nobuthi obungaba khona.Ukuncipha komsebenzi we-enzyme kungatholakala ngokuntuleka kofuzo, isifo sesibindi, ukonakala, ukungondleki, ukwehluleka kwezinso, ukusha, i-thirdtrimester yokukhulelwa, kanye nokulandela ukuhlinzwa kwe-cardiopulmonary bypasssurgeon.I-Ester hydrolysis ikhiqiza i-PABA, i-compounds ebhekele ukungezwani komzimba okuvamile kuma-anesthetics e-theester.I-Procaine ayisetshenziswa ngokwezihloko ngenxa yokungakwazi ukudlula kulwelwesi lwe-lipid futhi ithola ukusetshenziswa njenge-aninfiltration ejenti yolwelwesi lwesikhumba noma lwamafinyila, izinqubo ezifushane.I-Procaine iphinde isetshenziselwe ukuvimba izinzwa ezithintekayo futhi njenge-ejenti ye-epidural ukuze kuhlonzwe izimpawu zobuhlungu.


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