Trenbolone Cyclohexylmethylcarbonate CAS: 23454-33-3 11-trien-3-ọkan carbonate cyclohexylMethylcarbonate (8CI)

Ifihan kukuru:
Trenbolone (TRE) jẹ homonu assimilation amuaradagba sitẹriọdu ti o lo pupọ.O jẹ itọsẹ chemosynthetic ti o jọra si testosterone homonu ọkunrin ninu eto ati iṣẹ ṣiṣe.O le se igbelaruge amuaradagba kolaginni, mu yanilenu, mu isan, igbelaruge kalisiomu ati irawọ owurọ ninu egungun àsopọ, ati ki o le ṣee lo isẹgun lati toju àìdá onje àìdá ati osteoporosis, sugbon o jẹ awọn julọ nigbagbogbo lo iru ti idaraya stimulant.Ẹgbẹ bolone cyclohexyl methyl carbonate le ṣee lo bi agbedemeji sintetiki ti ẹgbẹ Bolone.
Igbaradi:
Ẹgbẹ bromcyclohexyl methyl carbonate ti pese sile bi atẹle:
3G17/3-hydroxy-estradiol-4,9, 11-triene-3-ọkan ti tuka ni pyridine ni 15℃ ati 0℃ labẹ agitation ati nitrogen bugbamu.Jeki awọn iwọn otutu laarin 0 ati 10 iwọn Celsius.Laiyara fi 50ml hexahydrobenzyl chloride Chemicalbook formate, lẹhinna gbona gbogbo adalu si iwọn otutu ibaramu, aruwo fun awọn wakati 2, lẹhinna dara si 0 ° C. Fi triethylamine kun ati ki o ru fun awọn iṣẹju 30 lati gbe iwọn otutu si ibaramu ki o si tú adalu esi sinu omi / yinyin adalu.O ti fa jade pẹlu methylene kiloraidi, ati pe apakan Organic ni a fi omi fo si didoju, ti o gbẹ pẹlu imi-ọjọ soda, ti a si yọ kuro labẹ igbale titi ti o gbẹ.Ajẹkù ti yapa nipasẹ chromatography lori gel silica, eluted pẹlu 4: 1 adalu benzene/ethyl acetate, ati recrystallized lati isopropyl ether/hexane adalu.Chromatography ti a ṣe lẹẹkansi lori silica gel, eluted pẹlu adalu benzene / ethyl acetate, ati nipari recrystallized lati cyclohexane ati petroleum ether lati gba 1.60g ẹgbẹ bromcyclohexyl methyl carbonate.Ọja naa han bi prism tiotuka ninu ethanol, ether, benzene, acetone, ati chloroform, ṣugbọn aifọkanbalẹ ninu omi, dilute acid, ati awọn ojutu lye.