Pressinoic Acid CAS:35748-51-7 CYS-TYR-PHE-GLN-ASN-CYS(DISULFIDE BRIDGE CYS1-CYS6)
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Pressinoic acid jẹ ọra acid ti a fihan lati ṣe bi antagonist ti o lagbara ti olugba GABAA.O ṣe idiwọ iṣẹ-ṣiṣe locomotor ati fa awọn ijagba ninu awọn ẹranko.Pressinoic acid tun jẹ onidalẹkun ti awọn aarun ajakalẹ-arun bii Herpes, influenza, ati rabies.Apapọ yii sopọ mọ nucleotide adenine lori olugba GABAA ati ṣe idiwọ awọn ions kiloraidi lati wọ inu sẹẹli nipasẹ didojukuro agbara omi.Ibaraẹnisọrọ ti pressinoic acid pẹlu olugba GABAA ṣe idiwọ iṣẹ-ṣiṣe neuronal inhibitory, eyiti o yori si ikọlu.Pressinoic acid le ṣee lo fun itọju warapa, Arun Parkinson ati awọn rudurudu iṣan miiran.Pressinoic acid jẹ agonist ti o lagbara ti olugba GABAA ti o le rii ni awọn homonu peptide gẹgẹbi vasopressin (homonu antidiuretic).O ti wa ni sise nipasẹ idasile mnu disulfide laarin awọn iṣẹku cysteine meji ni ọna amino acid rẹ.X-ray diffraction data ti han