awọn agbedemeji elegbogi 99% iyẹfun mimọ CAS 86386-73-4 Fluconazol
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Alaye ipilẹ
Fluconazole-D4 han bi funfun si ofeefee-funfun crystalline lulú ati ki o jẹ õrùn diẹ pẹlu itọwo kikorò.
O ti wa ni irọrun tiotuka ni glacial acetic acid, kẹmika tabi ethanol, ko ni itọka ninu omi ati pe o fẹrẹ jẹ insoluble ni ether pẹlu aaye yo jẹ 137 ~ 141.6 ℃, tabi aaye fifọ jẹ 138 ~ 140 ℃ (ti o wa lati ethyl acetate-hexane).
Lilo
Ọja yi je ti fluorinated triazole oogun antifungal pẹlu antifungal julọ.Oniranran jije iru bi ketoconazole sugbon antifungal aṣayan iṣẹ-ṣiṣe ti o ga ju ketoconazole.
Ilana iṣe rẹ jẹ nipasẹ idinamọ paati pataki ti awọ sẹẹli olu, enzymu ergosterol biosynthesis, didi idawọle ergosterol ati fifọ iduroṣinṣin ti ogiri sẹẹli olu, ni idinamọ siwaju idagbasoke ati ẹda wọn.
Ọja naa ni iṣẹ antifungal ti o lagbara lodi si Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum ati epidermophyton.
Kemikali Properties
Fluconazole-D4 jẹ Funfun si Paa-White Ri to
Nlo Fluconazole Aami (F421000).Ti a lo bi antifungal.
Nlo anticholinergic
Nlo Fluconazole-D4 ni a lo fun itọju awọn akoran olu.
Nlo A triazole oluranlowo antifungal gbooro-spekitiriumu.
Awọn itọkasi
Fluconazole (Diflucan) le ni gbigba dara julọ ati pe o ṣee ṣe ki o kere si hepatotoxic ju ketoconazole, ṣugbọn o jẹ gbowolori pupọ diẹ sii, akiyesi pataki ti a fun ni gigun ti itọju ailera fun pupọ julọ awọn arun olu.