Ohun elo Kemikali Organic Ohun elo Didara Giga Ipese taara Troparil CAS 74163-84-1 Fun Iwadii
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Troparil jẹ inhibitor reuptake dopamine ti o da lori phenyltropane ti o jẹ lati methylecgonidine.O ti wa ni a stimulant oògùn lo ninu ijinle sayensi iwadi.Ọna ti o wọpọ julọ ti troparil ni iyọ tartrate, ṣugbọn hydrochloride ati awọn iyọ naphthalenedisulfonate tun wa, ati ipilẹ ọfẹ.
A lo Troparil ninu iwadii imọ-jinlẹ sinu gbigbe gbigbe ti dopamine.Awọn fọọmu 3H-radiolabelled ti troparil ni a ti lo ninu eniyan ati ẹranko lati ṣe maapu pinpin awọn gbigbe dopamine ninu ọpọlọ.O tun lo fun iwadii ẹranko.
Troparil jẹ awọn akoko diẹ ti o lagbara ju kokeni lọ bi oludena atunṣe dopamine, ṣugbọn ko ni agbara bi oludena atunṣe serotonin, ati pe o ni iye akoko ti o lọ ni igba diẹ to gun, nitori oruka phenyl ti sopọ taara si oruka tropane nipasẹ kii- hydrolyzable erogba-erogba mnu.Aini isunmọ ester kan yọ iṣẹ anesitetiki agbegbe kuro ninu oogun naa, nitorinaa troparil jẹ itunra mimọ.Yi ayipada ninu aṣayan iṣẹ-ṣiṣe tun mu ki troparil die-die kere cardiotoxic ju kokeni.
Β-CPT
B-CPT
Troparil
2β-Carbomethoxy-3β-phenyltropane
2-beta-Methoxycarbonyl-3-beta-phenyltropane
(-)-2β-Carbomethoxy-3β-phenyltropane,WIN 35,065-2, tabiβ-CPT)
8-Azabicyclo(3.2.1) octane-2-carboxylicacid,8-methyl-3-phenyl-,methylester,
(Exo, exo) -8-methyl-3-phenyl-8-azabicyclo(3.2.1) octane-2-carboxylicacidmethylester
(Exo, exo) -8-methyl-3-phenyl-8-azabicyclo(3.2.1) octane-2-carboxylic acid methyl ester
8-Azabicyclo(3.2.1) octane-2-carboxylic acid, 8-methyl-3-phenyl-, methyl ester, (exo, exo)
8-Azabicyclo[3.2.1] octane-2-carboxylicacid, 8-Methyl-3-phenyl-, Methyl ester, (1R,2S,3S,5S) -rel-
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