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GHRP-2/Pralmorelin CAS: 158861-67-7 d-ala-β- (2-naphthyl) -d-ala-trp-d-phe-lys amide

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  • KỌRỌ RẸ:170851-70-4
  • Orukọ:GHRP-2/Pralmorelin
  • Ilana kemikali:C 45 H 55 N 9 O 6
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  • iwọn otutu ipamọ:-20°C
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  • Alaye ọja

    ọja Tags

    Lilo

    Pralmorelin (INN) (orukọ iṣowo GHRP Kaken 100; Awọn orukọ koodu idagbasoke tẹlẹ KP-102, GPA-748, WAY-GPA-748), ti a tun mọ ni pralmorelin hydrochloride (JAN) ati pralmorelin dihydrochloride (USAN), ati ni pataki, Growth homonu itusilẹ Peptide 2 (GHRP-2), aṣiwadi homonu idagba (GHS), ni a lo bi aṣoju iwadii ati tita ni fọọmu iwọn lilo ẹyọkan nipasẹ Kaken Pharmaceutical of Japan fun iṣiro aipe homonu idagba (GHD).

    Pralmorelin jẹ oogun peptide sintetiki pẹlu iṣẹ ṣiṣe ẹnu.Ni pato, o jẹ afọwọṣe ti methoxyenkephalin pẹlu amino acid lẹsẹsẹ D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. O ṣe bi auxin ti o tu silẹ peptide / idagba homonu secretin receptor ( GHSR) agonist ati pe o jẹ oogun akọkọ ti iru rẹ lati ṣafihan sinu ile-iwosan.Isakoso nla ti oogun naa pọ si ni pataki awọn ipele homonu idagba pilasima (GH) ati ni igbẹkẹle fa ebi ati mu gbigbe ounjẹ pọ si ninu eniyan.

    A tun ṣe iwadi Pralmorelin fun GHD ati kukuru kukuru (pituitary dwarfism) ati ti tẹ awọn idanwo ile-iwosan alakoso II fun awọn itọkasi wọnyi, ṣugbọn nikẹhin ko ṣe si ọja.Eyi le jẹ nitori pe agbara pramoline lati mu awọn ipele GH pilasima pọ si jẹ kekere ni pataki ni awọn alaisan GHD ju awọn eniyan ti o ni ilera lọ

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