Hexapeptide Anti-Aging-11 CAS 161258-30-6 Din hihan awọn wrinkles dinku
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Orukọ ti o wọpọ | Hexapeptide-11 | English orukọ | Hexapeptide-11 |
---|---|---|---|
nọmba CAS | 161258-30-6 |
Ilana molikula | C36H48N6O7 |
---|---|
Ìwúwo molikula | 676.80200 |
Iwọn deede | 676.35800 |
PSA | 201.71000 |
LogP | 4.09300 |
Lilo:
Hexapeptide-11 jẹ modulator aramada ti nẹtiwọọki proteostasis ninu awọn fibroblasts diploid eniyan.
Hexapeptide-11 dinku hihan awọn ila ti o dara ati awọn wrinkles, ṣiṣe eyi jẹ afikun ti o dara julọ si gbogbo iru itọju awọ ara ati awọn ọja ti ogbologbo.O ni eto alailẹgbẹ ti amino acids ti o ṣe iranlọwọ lati ṣe afọwọyi awọn ipele collagen ati igbelaruge rirọ ninu awọ ara.
Ifihan ti fibroblasts si Hexapeptide-11 iwọn igbega igbega ati imuṣiṣẹ ti o gbẹkẹle akoko ti proteasome, autophagy, chaperones ati awọn jiini ti o ni ibatan awọn idahun antioxidant.Pẹlupẹlu, o ṣe agbega ikojọpọ iparun ti o pọ si ti Nrf2;Awọn ipele ikosile ti o ga julọ ti awọn subunits amuaradagba proteasomal ati alekun awọn iṣẹ peptidase proteasome.Ni ila pẹlu awọn awari wọnyi a ṣe akiyesi pe Hexapeptide-11 funni ni aabo pataki ni awọn fibroblasts lodi si aibalẹ oxidative-stress-mediated premature cellular senescence, lakoko ti o wa ninu vivo awọn igbelewọn abuku awọ ara ni awọn koko-ọrọ eniyan o dara si rirọ awọ ara.