Ukunciphisa umzimba Semaglutide CAS 910463-68-2
Inkcazo
I-Semaglutide (910463-68-2) iyeza elichasene nesifo seswekile elithengiswa phantsi kwamagama eebrand ezifana ne-Ozempic, Wegovy, kunye ne-Rybelsus.Isetyenziselwa ukuphatha uhlobo lwe-2 yeswekile kunye nokulawula ubunzima obungapheliyo.Ichiza lisebenza ngokufana ne-glucagon-like peptide-1 (GLP-1) ngokwandisa ukukhutshwa kwe-insulin, okukhokelela ekuphuculweni kwemetabolism yeswekile.Isasazwa njenge-metered subcutaneous injection kwipeni ezaliswe kwangaphambili, okanye njengefom yomlomo.Enye yeenzuzo zayo ngaphezu kwamanye amachiza e-antidiabetic kukuba inexesha elide lesenzo, ngoko ke, isitofu esikanye kuphela ngeveki sanele.
Usebenzisa
I-Semaglutide isetyenziselwa ukulawula uhlobo lwe-2 yeswekile kunye nokutshintsha kwendlela yokuphila, njengezithintelo zokutya kunye nokunyuka komzimba.Ikwasebenza ngokucothisa intshukumo yokutya ngesisu kwaye inokunciphisa umdla wokutya kwaye ibangele ukwehla kobunzima.Akuzange kubekho iingxelo ezipapashiweyo ze-hepatotoxicity ezibangelwa unyango lwe-semaglutide.
Indlela yokwenza
I-Semaglutide yi-glucagon efana ne-peptide-1 i-receptor agonist.Yandisa ukuveliswa kwe-insulin, ihomoni ehlisa izinga leswekile yegazi.Ikwabonakala ngathi ikhulisa ukukhula kweeseli ze-β kwi-pancreas, eziyindawo yokuvelisa i-insulin.Ikwanqanda iglucagon, eyihomoni eyandisa iswekile yegazi.Ukongeza kunciphisa ukutya ngokunciphisa ukutya kunye nokunciphisa ukugaya esiswini.Ngale ndlela kunciphisa amafutha omzimba.
Umsebenzi webhayoloji
I-Semaglutide (Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217), i-glucagon-efana ne-peptide 1 (GLP-1) analogue, i-GLP-1 ye-receptor agonist enokukwazi ukunyanga uhlobo lwe-2 yeswekile mellitus. (T2DM).