Funda malunga ne-hyaluronic acid kunye

Amacandelo aphambili

Iasidi yeHyaluroniki yi-acidic mucopolysaccharide.Ngowe-1934, uMeyer, unjingalwazi wezifundo zamehlo kwiYunivesithi yaseColumbia eUnited States, waqala wakhetha le nto kwi-bovine vitreous.I-asidi ye-Hyaluroniki, kunye nesakhiwo sayo esisodwa se-molecular kunye neempawu zomzimba kunye neekhemikhali, ibonisa iindidi zemisebenzi ebalulekileyo yomzimba emzimbeni, njengamalungu okuthambisa, ukulawula ukungeneka kodonga lwe-vascular, ukulawula ukusasazwa kunye nokusebenza kweeprotheni, amanzi kunye ne-electrolytes, kunye ukukhuthaza ukuphiliswa kwenxeba.

Injongo ephambili
Amachiza e-biochemical anexabiso eliphezulu leklinikhi asetyenziswa ngokubanzi kwimisebenzi eyahlukeneyo yamehlo, njengokufakelwa kwe-lens, ukutshintshwa kwe-corneal kunye noqhaqho lokulwa ne-glaucoma.Ingasetyenziselwa ukunyanga isifo samathambo kunye nokukhawulezisa ukuphiliswa kwenxeba.Xa isetyenziswa kwizinto zokuthambisa, inokudlala indima ekhethekileyo ekukhuseleni ulusu, ukugcina ulusu lufumile, lugudileyo, luthambile, luthambile kwaye lunwebeka, kwaye lunemisebenzi yokuchasana nemibimbi, ukulwa nemibimbi, ubuhle kunye nokhathalelo lwempilo, kunye nokubuyisela imisebenzi yempilo yolusu.

Usasazo lokuhlela oluluncedo
Iimveliso zamachiza
I-asidi ye-Hyaluroniki iyona nto iphambili yezicubu ezidibeneyo ezifana ne-intercellular substance yomntu, umzimba we-vitreous, i-synovial fluid edibeneyo, njl. .Iimolekyuli ze-Hyaluroniki ze-asidi ziqulethe inani elikhulu lamaqela e-carboxyl kunye ne-hydroxyl, eyenza i-intramolecular kunye ne-intermolecular hydrogen bonds kwisisombululo esinamanzi, okwenza kube nefuthe elinamandla lokugcina amanzi kwaye inokudibanisa amaxesha angaphezu kwama-400 amanzi ayo;Kwinqanaba eliphezulu, isisombululo saso samanzi sine-viscoelasticity ebalulekileyo ngenxa yesakhiwo sothungelwano semfundo ephakamileyo eyinkimbinkimbi eyenziwa yintsebenziswano ye-intermolecular.I-asidi ye-Hyaluroniki, njengenxalenye ephambili ye-matrix ye-intercellular, ithatha inxaxheba ngokuthe ngqo kulawulo lokutshintshiselwa kwe-electrolytes ngaphakathi nangaphandle kweseli, kwaye idlala indima njengesihluzo solwazi lomzimba kunye ne-molecular.Iasidi yeHyaluroniki ineempawu ezizodwa zomzimba kunye neekhemikhali kunye nemisebenzi yomzimba, kwaye isetyenziswe ngokubanzi kumayeza.
I-asidi ye-Hyaluroniki ingasetyenziswa njenge-agent ye-viscoelastic yokufakelwa kwe-lens ye-ophthalmic intraocular, njenge-filler yotyando oludibeneyo olufana ne-osteoarthritis kunye ne-rheumatoid arthritis.Isetyenziswa ngokubanzi njengento ephakathi kumathontsi esweni, kwaye ikwasetyenziselwa ukuthintela ukuncamathela kwangemva kokusebenza kunye nokukhuthaza ukuphiliswa kwamanxeba esikhumba.I-compound eyenziwe yi-reaction ye-hyaluronic acid kunye namanye amachiza idlala indima yokukhululwa ngokukhawuleza kwiyeza, elinokuthi lifezekise injongo yokukhululwa okujoliswe kuyo kunye nexesha.Ngokuphuhliswa kobuchwepheshe bezonyango, i-hyaluronic acid iya kusetyenziswa ngokubanzi kwiyeza.
Iimveliso ezityiwayo
Umxholo we-hyaluronic acid emzimbeni womntu malunga ne-15g, edlala indima ebalulekileyo kwimisebenzi ye-physiological yabantu.Umxholo we-hyaluronic acid esikhumbeni uyancitshiswa, kwaye umsebenzi wokugcinwa kwamanzi wesikhumba uyancipha, okwenza ukuba kubonakale kunzima kwaye kushwabene;Ukuncipha kweasidi ye-hyaluronic kwezinye izihlunu kunye namalungu kunokukhokelela kwi-arthritis, i-arteriosclerosis, ukuphazamiseka kwepulse kunye ne-brain atrophy.Ukuncipha kweasidi ye-hyaluronic emzimbeni womntu kuya kubangela ukuguga kwangaphambi kwexesha.