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Izicatshulwa zezityalo zendalo ze-CAS 51-34-3 Scopolamine

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  • Igama eliqhelekileyo:I-Scopolamine
  • Inombolo yeCAS:51-34-3
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    Ulwazi olusisiseko

    51-34-3

    I-Scopolamine(i-hyoscine) ifumaneka kumalungu ahlukeneyo e-Solanaceae (umzekelo, i-H. niger, i-Duboisia myoporoides, i-Scopolia spp., kunye ne-Datura metel).I-Scopolamine ngokuqhelekileyo iba yodwa kutywala bukamama obushiyekileyo kukwahlulwa kwe-hyoscyamine.

    I-Hyoscine ligama elidala lale alkaloid, nangona i-scopolamine ligama elamkelekileyo e-United States.I-Scopolamine yi-levo component yomxube we-racemic owaziwa ngokuba yi-atroscine.I-alkaloid i-racemized ngokulula kubukho be-alkali edibeneyo.

    I-alkaloid yenzeka ngohlobo lwe-levorotatory, viscousliquid enyibilika kancinane kuphela emanzini kodwa i-solublein alcohol, i-chloroform, okanye i-ether.Yenza i-crystalline salts kunye nee-asidi ezininzi, kunye ne-hydrobromide yeyona nto izinzile kwaye ithandwa kakhulu.Unyibiliko olumanzi lwe-hydrobromide equlethe i-10% ye-mannitol kuthiwa ayithandeki kangako ukubola kunezisombululo ezingakhuselekanga.

    I-Pharmacology

    I-Scopolamine butylbromide, i-scopolamine elungisiweyo, i-peripheral anti-choline drug;ayigcini nje ngokugudisa i-muscle spasm kodwa iphinde ithintele i-ganglion kunye ne-neuromuscular junction kwaye inefuthe elibuthathaka kwiziko.Eli chiza lineziphumo ezinamandla kwi-intestinal smooth muscle spasm kune-atropine kunye ne-anisodamine;inokukhetha ukukhulula umjelo wesisu, i-biliary tract, kunye ne-urinary tract spasm egudileyo yezihlunu kwaye inqande i-peristalsis yayo.

    I-Scopolamine butylbromide ineempembelelo ezincinci entliziyweni, kumfundi, kunye ne-salivary gland, ngoko ke ayifane ibangele uvuyo oluphakathi kwe-nervous, ukuhlanjululwa, ukuvinjelwa kokuphuma kwamathe, kunye nezinye iziphumo ezibi, ezingafaniyo ne-atropine.

    I-Scopolamine butylbromide ngumchasi we-M cholinergic receptor, imiphumo yayo ye-pharmacological ifana ne-atropine, kodwa ineempawu zayo ezinenzuzo ebonakalayo ekuphuculeni i-microcirculation yegazi.

    I-CAS 94-15-5
    Levamisole
    Levamisole

    Ukusetyenziswa

    1. I-Scopolamineisetyenziselwa phantse imiqondiso efanayo ne-atropine, kodwa kufuneka kuqatshelwe ukuba inesiphumo sokuthomalalisa kwimisebenzi yemoto, kwaye iyacetyiswa kunyango lweempawu zeParkinsonian.

    2. i-cholinergic (i-ophthalmic).


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