I-Myomodulin CAS: 110570-93-9 H-Pro-Met-Ser-Met-Leu-Arg-Leu-NH2

inkcazelo emfutshane:

INOMBOLO YECASS:110570-93-9

Igama:Myomodulin

Ifomula yemichiza:I-C36H67N11O8S2

ifom:umgubo

Ubuninzi :1.38±0.1 g/cm3(Kuxelwe kwangaphambili)

pka:12.79±0.46(Kuxelwe kwangaphambili)

ubushushu bokugcina:−20°C

Ubunzima beMolar:846.11600

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Ukusetyenziswa

I-Neuropeptide myodulin, i-peptide encinci ye-cardiac esebenzayo (SCP) kunye neprotheni ye-buccal isasazwa ngokubanzi kwi-phylum mollusca kwaye inemisebenzi ebalulekileyo ye-physiological.Apha sichaza ukuhanjiswa okucacileyo kweklasi nganye ye-peptide kwinkqubo ye-nervous central (CNS) ye-Lymnaea stagnalis ngokusebenzisa ubuchule be-immunocytochemical ngokudibanisa nedayi yokubhala kwi-neurons echongwe yi-electrophysiology.Sinika ingxelo malunga nokuba yedwa kunye nokubonakaliswa kwesakhiwo se-A Lymnaomodulin PMSMLRLamide, efana ne-myomodulin A evela kumvundla wolwandle.I-Myomodulin immunoreactivity ifumaneka kuyo yonke i-ganglia ye-11, izicubu zabo ezidibeneyo, kunye ne-peripheral nerves.Kwiimeko ezininzi, i-myomodulin immunoreactivity ibonakala kumaqela ee-neurons ezibonisa i-FMRFamide-like peptides, kodwa nakwinani elikhulu lezinye ii-neurons.Uvavanyo lokulebhile kabini lubonise ukunganyangeki kwe-myomodulin kwi-visceral white interneurons ebandakanyeka kulawulo lwe-cardiopulmonary.I-Scp-efana ne-immune reactivity ikhona kuyo yonke i-ganglia, kwaye ii-assays zokuleyibhile kabini zibonisa ukuba inxulunyaniswa nokucaca kweqela leexons ezahlukeneyo ezichazwe ngokwahlukileyo kwi-CNS yofuzo lwe-FMRFamide kwiindawo ezininzi.Nangona kunjalo, iimpawu ze-antiserum ezimbini ze-SCP ezisetyenziswe kolu phononongo zicebisa ukuba ziphendule nge-FMRFamide kunye ne-n-terminal eyandisiweyo ye-FmrFamide-like peptides.I-preadsorption ekhethiweyo kusetyenziswa ezi peptides ezinqamlezayo zibangele ukupheliswa kokungcola okubanzi kunye nokugcinwa kwe-SCP eyinyani ye-immune reactivity kuphela kwi-buccal kunye ne-foot ganglia.I-Buccal protein immunoreactivity yayilinganiselwe kwi-buccal kunye ne-foot ganglia.Ayihambelani nokuhanjiswa kwe-myomodulin okanye i-SCP.Uninzi lwamaqela empendulo ye-immune afumaneka kwi-foot ganglion.Ayihambelani nokuhanjiswa kwe-myomodulin okanye i-SCP.Uninzi lwamaqela empendulo ye-immune afumaneka kwi-foot ganglion.Ayihambelani nokuhanjiswa kwe-myomodulin okanye i-SCP.Uninzi lwamaqela empendulo ye-immune afumaneka kwi-foot ganglion.