I-Methasteron CAS NO: 3381-88-2 17α-DiMethyldihydrotestosterone NSC 40490

intshayelelo

I-Methyldrostenone yi-anabolic androsteroid eyenziwe yi-hormone ye-steroid esebenzayo i-Methyldrostanolone.Le yi-anabolic steroid ephuma kwi-DHT ekwayindlela yokuguqulwa kwesakhiwo se-drostenone.

imbali

I-synthesis ye-metestosterone yaqala ukukhankanywa kwiincwadi kwi-1956, xa i-Syntex Corporation yenza uphando ngokufunyanwa kwe-compound ene-antitumor properties.Kwaqala ukukhankanywa kwaye kwacaciswa kwinqaku lejenali yophando ka-1959, eyayixubusha iindlela zayo zokwenziwa ngokweenkcukacha ngakumbi, yaqinisekisa iipropathi zayo ze-tumor suppressor, kwaye yaphawula ukuba "yi-agent esebenzayo yomlomo esebenzayo ye-anabolic ebonisa kuphela umsebenzi obuthathaka kunye ne-androgenic."Imilinganiselo elandelayo ye-anabolic kunye nomsebenzi we-androgenic we-metestosterone yapapashwa kwi-Androgen kunye neziyobisi ze-anabolic e-Vida, isalathiso esiphelelwe yisikhathi kodwa sisesigxina, esichaza ukuba i-metestosterone ine-oral bioavailability methyltestosterone kunye ne-400% njenge-anabolic kunye ne-20% njenge-androgen, Ivelisa umlinganiselo we-Q. ye-20 (i-anabolic kwi-androgen ratio), ethathwa njengephezulu kakhulu.