Ipamorelin CAS: 170851-70-4 IPAMORELIN;AIB-HIS-D-NAL(2)-D-PHE-LYS-NH2
Ukusetyenziswa
I-Ipamorelin (INN) (ikhowudi yophuhliso ye-NNC 26-0161) i-agonist ekhethiweyo ye-peptide ye-auxin ekhupha i-peptides / i-somatosecretin receptors (GHS) kunye ne-somatosecretin.I-pentapeptide kunye nokulandelelana kwe-amino acid Aib-His-D-2-Nal - D-Phe -Lys-NH 2, evela kwi-GHRP-1.
I-Ipamorelin inyusa kakhulu i-plasma ye-hormone yokukhula (GH) kwizilwanyana kunye nabantu.Ukongezelela, i-ipamorelin ivuselele ubunzima kwizilwanyana.Njenge-pralmorelin kunye ne-GHRP-6, i-ipamorelin ayichaphazeli iprolactin, i-follicle-stimulating hormone (FSH), i-luteinizing hormone (LH), okanye i-thyrotropin (TSH) amanqanaba.Nangona kunjalo, ngokungafani ne-pramoline (GHRP-2) kunye ne-GHRP-6, kodwa ifana ne-hormone yokukhula ekhupha i-hormone (GHRH), i-iparerelin ayikhuthazi ukukhutshwa kwe-hormone ye-adrenocorticotropic (ACTH) okanye i-cortisol kwaye ikhethe kakhulu ukukhupha i-GH secretion kuphela.
I-Ipamorelin ekuqaleni yaphuhliswa nguNovo Nordisk kwaye yaqhuba izilingo zeklinikhi zesigaba se-II ngokwayo njengonyango lwe-lobstruction emva kokusebenza, kodwa yayekwa ngenxa yokungabikho kokusebenza kakuhle.
I-Ipamorelin isetyenziswe ngabadlali njengeyeza lokuphucula ukusebenza.