I-Organic Chemical Material ekrwada Umgangatho ophezulu weFactory Ubonelelo ngokuthe ngqo Troparil CAS 74163-84-1 kuPhando
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I-Troparil yi-phenyltropane-based dopamine reuptake inhibitor ephuma kwi-methylecgonidine.Lichiza elivuselelayo elisetyenziswa kuphando lwezenzululwazi.Uhlobo oluqhelekileyo olusetyenziswayo lwe-troparil yityuwa ye-tartrate, kodwa i-hydrochloride kunye ne-naphthalenedisulfonate salts ziyafumaneka, kunye nesiseko samahhala.
I-Troparil isetyenziswa kuphando lwezenzululwazi kwi-dopamine reuptake transporter.Iifom ze-3H-radiolabelled ze-troparil zisetyenzisiwe ebantwini nakwizilwanyana ukwenza imephu yokusasazwa kwabathuthi be-dopamine engqondweni.Ikwasetyenziselwa uphando ngezilwanyana.
I-Troparil inamandla amaxesha ambalwa ngaphezu kwe-cocaine njenge-dopamine reuptake inhibitor, kodwa ingaphantsi kwamandla njenge-serotonin reuptake inhibitor, kwaye inexesha elithatha amaxesha ambalwa ubude, kuba umsesane we-phenyl uqhagamshelwe ngokuthe ngqo kwiringi ye-tropane ngokusebenzisa i-non- ibhondi yekhabhoni ye-hydrolyzable.Ukungabikho konxibelelwano lwe-ester kususa isenzo se-anesthetic yendawo kwiyeza, ngoko ke i-troparil yinto ecocekileyo evuselelayo.Olu tshintsho kumsebenzi lwenze ukuba i-troparil ibe ne-cardiotoxic kancinane kune-cocaine.
Β-CPT
B-CPT
Troparil
I-2β-Carbomethoxy-3β-phenyltropane
I-2-beta-Methoxycarbonyl-3-beta-phenyltropane
(–) -2β-Carbomethoxy-3β-phenyltropane,WIN 35,065-2, orβ-CPT)
8-Azabicyclo (3.2.1) octane-2-carboxylicacid,8-methyl-3-phenyl-,methylester,
(Exo,exo)-8-methyl-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylicacidmethylester
(Exo,exo)-8-methyl-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester
8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 8-methyl-3-phenyl-, methyl ester, (exo,exo)-
8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 8-Methyl-3-phenyl-, Methyl ester, (1R,2S,3S,5S)-rel-
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