I-China yokuthengisa okushushu kwe-CAS 151767-02-1 Montelukast sodium singulair mk-476

I-China yokuthengisa okushushu CAS 151767-02-1 Montelukast sodium singulair mk-476 Umfanekiso ofakiweyo

inkcazelo emfutshane:

Indawo yokubilisa: 750.5ºC ku-760mmHg

Indawo yokunyibilika: 115 °C(dec.)

Ifomula yemolekyuli: C35H35ClNNaO3S

Ubunzima bemolekyuli: 608.165

Indawo edanyazayo: 407.7ºC

Ubunzima obuchanekileyo: 607.192383

PSA: 98.55000

LogP: 7.61330

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

I-Montelukast sodium yinto yomlomo kunye nesebenzayo ekhethiweyo ye-leukotriene receptor antagonist, enokuthintela ngokukodwa i-cysteineyl leukotriene receptors.Yaphuhliswa ngempumelelo nguMerck waseJamani.Ngo-1997, yasungulwa eCanada, eFinland, Ifumaneka eMexico.Ilungele ukuthintela kunye nonyango lwexesha elide lwe-asthma kubantu abadala kunye nabantwana, kubandakanywa nokuthintela iimpawu ze-asthma zasemini nasebusuku, ukunyangwa kwezigulane ze-asthma-sensitive asthma, kunye nokuthintela i-bronchoconstriction eyenziwa ngumzimba.Iimpawu ze-rhinitis ye-allergic ngamaxesha kwizigulane ezingasebenziyo okanye ezinganyamezeliyo.