I-Catestatin Peptide CAS:142211-96-9 I-Catestatin (iinkomo) I-CATESTATIN
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Ukusetyenziswa
Ziziphi iipeptides ze-casein:
Iipeptide zeCasein ziimolekyuli ezincinci zepeptides ezisebenzayo ezifunyenwe yi-enzymolysis evela kwi-casein.Uvavanyo oluyeleleneyo lubonakalise ukuba i-casein peptides ineziphumo zokuthoba uxinzelelo lwegazi, ukwehlisa iswekile yegazi, i-antithrombus kunye nokuphucula ukulala.I-Casein yenza malunga ne-80% yeprotheyini epheleleyo yobisi, enye yemithombo ebalulekileyo yeprotheyini yomgangatho ophezulu kubomi bemihla ngemihla baBantu.I-Casein iqulethe ii-amino acids ezininzi ezibalulekileyo ekukhuleni komntu kwaye ingumthombo olungileyo we-bioactive peptides.
Ukusebenza kunye nesenzo:
Kuye kwangqinwa ukuba i-casein peptide inokuthintela i-angiotensin converting enzyme (ACE).I-casein peptide inokuthintela umsebenzi we-angiotensin ukuguqula i-enzyme (ACE), ukunciphisa i-angiotensin Ⅱ ukuveliswa kunye nokungasebenzi kwe-kinin, ukuze kuphunyezwe injongo yokunciphisa uxinzelelo lwegazi, kwaye ayichaphazeli uxinzelelo lwegazi oluqhelekileyo, olulungele ulawulo lwexesha elide.Kungabonwa ukuba i-casein peptide yinto ekhuselekileyo, yendalo kunye nesebenzayo ye-antihypertensive yokutya okusempilweni.Ukongeza ekunciphiseni uxinzelelo lwegazi, i-casein peptides inefuthe lokunciphisa iswekile yegazi.Isifo seswekile sisifo se-endocrine kunye ne-metabolic esibangelwa kukunqongophala kwe-insulin okanye ukunqongophala kwesalamane okuphawulwa sisifo seswekile ephezulu, kwaye siphakathi kwezona zizathu zilishumi ziphezulu zokufa emhlabeni.Ukongeza, i-casein peptides nayo ineempembelelo ze-antithrombotic.I-Casein peptide inokuthintela umsebenzi we-thrombin, yokwandisa ixesha le-fibrinogen coagulation, inhibit ngakumbi i-platelet agglutination, kwaye ngaloo ndlela inqanda i-thrombosis.I-Casein peptide inomsebenzi wokukhuthaza ubuthongo, obunokunciphisa ixesha lokulala, ukwandisa ixesha elipheleleyo lokulala, kunye nokuphucula ubunzima bokulala, ukuvuka kwangethuba, ukulala okulula kunye nezinye iingxaki.YiVangeli uninzi lwabantu abanengxaki yokulala.
Umsebenzi webhayoloji:
I-Catestatin i-peptide ye-cationic hydrophobic equkethe i-21 i-amino acid intsalela.ICatestatin yipeptide engapheliyo elawula ukusebenza kwentliziyo kunye noxinzelelo lwegazi.I-Catestatin ngumchasi we-nicotinic ongenakukhuphisana ovimbela ukukhululwa kwe-catecholamines ngokusebenzisa i-nicotinic acetylcholine receptors (nAChRs).