Inombolo ye-CAS;1631074-54-8 SGT-78 CUMYL-4CN-BINACA CUMYL-CYBINACA
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Ukusetyenziswa
I-CUMYL-4CN-BINACA (eyaziwa nangokuthi yi-CUMYL-CYBINACA okanye i-SGT-78) i-synthetic cannabinoid esekelwe kwi-indazol-3-formamide ethe yathengiswa kwi-intanethi njengeyeza elikhethekileyo.I-agonist enamandla ye-cannabinoid receptors CB 1 kunye ne-CB 2, kunye ne-vitro EC 50 ixabiso le-0.58 nM kunye ne-6.12 nM, ngokulandelanayo.Kwiigundane, i-CUMYL-4CN-BINACA ivelisa i-hypothermia kwaye ibangela ukuxubha ngesenzo se-CB 1 receptor, kwaye iingxelo ze-anecdotal zibonisa umthamo osebenzayo malunga ne-0.1 mg kubantu.
I-CUMYL-4CN-BINACA i-metabolized ukuvelisa i-cyanide, iphakamisa inkxalabo malunga nobutyhefu besibindi.Kukho ingxelo enye ye-hyperthermia, i-rhabdomyolysis kunye nokungaphumeleli kwezintso ezinxulumene nokusetyenziswa kwayo.