2-Fluoroamphetamine CAS NO : 1716-60-5
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Ukusetyenziswa
I-2-fluamphetamine (2-FA) lichiza elivuselelayo kusapho lwe-amphetamine kwaye lithengiswe njengechiza elikhethekileyo.I-2-Fluoroamphetamine yohlukile ku-3- kunye no-4 -i-fluoroamphetamine kwindawo yee-athom ze-fluorine kwiringi yevumba elimnandi, izenza ii-isomers ezikwindawo enye kwenye.Ukutshintsha iiathom ze-hydrogen ngeeathom ze-fluorine kwezinye iikhompawundi ukuququzelela ukudlula kwisithintelo segazi-ingqondo, njengoko kunqweneleka kumachiza enkqubo ye-nervous ephakathi, yinto eqhelekileyo enikwa ngoku kufakwa endaweni yezibonelelo ngenxa yokwanda okuhambelanayo kwi-lipophilicity.
i-pharmacology
I-Anorexia dose (50% inhibition of food intake within 2 hours, given 1 hour in advance) = 15 mg/kg (iigundane; Oral).
I-analgesic dose (50% inhibition of tail-clip reaction) = 20 mg / kg (mouse; ip).
Impembelelo kuxinzelelo lwegazi: I-0.5 mg / kg (iigundane; i-Intravenous) inokunyusa uxinzelelo lwegazi nge-29 millimeters.