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GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide

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  • NOMORO YA CAS:170851-70-4
  • Lebitso:GHRP-2 / Pralmorelin
  • Foromo ea lik'hemik'hale:C 45 H 55 N 9 O 6
  • Sebaka sa ho qhibiliha :149 - 151°C
  • mocheso oa polokelo.:−20°C
  • pka:13.40±0.46(E boletsoeng esale pele)
  • Sebaka se belang :1265.3±65.0 °C(E boletsoeng esale pele)
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    Tšebeliso

    Pralmorelin (INN) (lebitso la khoebo GHRP Kaken 100; Mabitso a khoutu ea pele ea nts'etsopele ea KP-102, GPA-748, WAY-GPA-748), e tsejoang hape e le pralmorelin hydrochloride (JAN) le pralmorelin dihydrochloride (USAN), mme haholoholo, Khōlo. Hormone e lokollang Peptide 2 (GHRP-2), secretagotor ea kholo ea hormone (GHS), e sebelisoa e le moemeli oa ho hlahloba le ho rekisoa ka mokhoa o le mong oa tlhahiso ea tekanyo ea Kaken Pharmaceutical ea Japane bakeng sa tlhahlobo ea khaello ea hormone ea ho hōla (GHD).

    Pralmorelin ke sethethefatsi sa maiketsetso sa peptide se nang le ts'ebetso ea molomo.Ka ho khetheha, ke analogue ea methoxyenkephalin e nang le tatellano ea amino acid D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. E sebetsa e le auxin e lokollang peptide / kgolo ea hormone secretin receptor ( GHSR) ke sethethefatsi sa pele sa mofuta oa sona ho kenngoa tleliniking.Tsamaiso e matla ea sethethefatsi e eketsa haholo maemo a "plasma growth hormone" (GH) 'me ka botšepehi e baka tlala le ho eketsa ho ja lijo ho batho.

    Pralmorelin e ntse e ithutoa bakeng sa GHD le boemo bo bokhutšoane (pituitary dwarfism) mme e kene litekong tsa kliniki tsa phase II bakeng sa matšoao ana, empa ha ho mohla e kileng ea fihla 'marakeng.Sena se kanna sa bakoa ke hore bokhoni ba pramoline ba ho eketsa maemo a GH ho plasma bo tlase haholo ho bakuli ba GHD ho feta ho batho ba phetseng hantle.

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