CAS 52232-67-4 Teriparatide acetate Activator Teriparatide
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Sebopeho:
Lebitso le tloaelehileng | Teriparatide Acetate | Lebitso la Senyesemane | pTH (1-34) (motho) letsoai la acetate |
---|---|---|---|
Nomoro ea CAS | 52232-67-4 |
Mokhoa oa limolek'hule | C181H291N55O51S2 |
---|---|
Boima ba molek'hule | 4177.77000 |
Litšobotsi tsa ponahalo | phofo |
Maemo a polokelo | E tiisitsoe, boloka ho -20 ºC |
Botsitso | Ha ho na ho bola, ha ho na likarabelo tse kotsi tse tsejoang haeba li sebelisoa le ho bolokoa ho latela litlhaloso |
Tšebeliso:
Teriparatide ke activator ea PHT e susumetsang tlhahiso e amanang le G-protein cyclic monophosphate.
Teriparatide e boetse e tsejoa e le recombinant human parathyroid hormone (1-34) mme e bonts'a litlamorao tsa anabolic lesapong.Teriparatide ke sethethefatsi se khahlanong le ho fokola ha masapo se sebelisoang ho phekola lefu la ho fokola ha masapo;ha e bontše molemo o khahlanong le resorptive, empa e susumetsa ho thehoa ha masapo le ho eketsa matla a masapo.Teriparatide e kenya tšebetsong mokelikeli oa PTH1.Maemong a kliniki, teriparatide e fokotsa ho robeha ha lesapo la mokokotlo le bohloko ba mokokotlo mme e eketsa letsoalo la lesapo la mokokotlo oa lumbar.Liseleng tsa stromal tsa mouse, teriparatide e laola polelo ea osterix le Runx2;ka mehlala ea liphoofolo tse pentiloeng, motsoako ona o eketsa kholo ea osteoblast le ho ntlafatsa pholiso ea fracture.