C-Telopeptide CAS;162929-64-8 L-Arginine L-α-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-α-aspartylglycylglycyl-
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Tšebeliso
C-terminal peptide (CTX), eo hape e tsejoang e le carboxy-terminal collagen crosslinking, ke C-terminal peptide ea fibrous collagens joalo ka mofuta oa I le mofuta oa II.E sebelisoa e le biomarker ho serum ho lekanya phetoho ea masapo.E ka sebelisoa ho thusa baoki hore ba tsebe hore na mokuli o arabela joang kalafong e sa buuoeng, hammoho le ho hlahloba kotsi ea ho ba le mathata nakong ea pholiso ka mor'a ho buuoa.[1] Teko ea matšoao a CTX, e bitsoang Serum CrossLaps, e tobile haholo bakeng sa ho ts'oaroa ha masapo ho feta tlhahlobo efe kapa efe e teng hona joale.
Mathoasong a lilemo tsa bo-2000, ho ile ha hlokomeloa kamano pakeng tsa tšebeliso ea bisphosphonate le tšenyo ea 'mele ea masapo.Thibelo e matla ea ts'ebetso ea osteoclast ka phekolo ea bisphosphonate e ka fella ka ho hatelloa ha lesapo le tloaelehileng, ho fella ka ho folisa maqeba ka mor'a tsietsi (e kang opereishene ea meno), esita le ho pepeseha ha masapo a sa foleng ka boithatelo.Hobane bisphosphonate e khethoa ka ho khetheha masapong a nang le phetoho e phahameng, maemo a bisphosphonate mohlahare a ka 'na a phahama ka mokhoa o ikhethileng.
Ka lebaka la ho kenngoa ha meno, palo e ntseng e eketseha ea bakuli ba meno e ntse e fumana phekolo e amanang le ho folisoa ha masapo a molomo, tse kang ho kenngoa ha ho buuoa le ho kenngoa masapo.Ho hlahloba kotsi ea osteonecrosis ho bakuli ba nkang li-bisphosphonates, Rosen o ile a hlahisa CTX biomarker ka 2000.