Anti-Estrogen E Atlehang Exemestane / Aromasin Powder Bakeng sa ho Fumana mesifa CAS 107868-30-4
Exemestane(Aromasin)Lintlha tsa Sehlahisoa
Lebitso la Sehlahisoa: Exemestane
Mantsoe a tšoanang: Aromasin
CAS: 107868-30-4
MF: C20H24O2
MW: 296.4
mp: 155.13°C
mocheso oa polokelo: Boloka ho -20°C
ponahalo: bosweu ho isa bosehla bo bobebe ba kristale phofo
Tlhaloso:
Aromasin e sebelisoa ho loantša mofetše oa matsoele le ho phahamisa testosterone 'meleng.
Exemestane e thibela mokhoa oa aromatisation.Kahoo e theola tekanyo ea estrogen 'meleng.Ka kankere ea matsoele ea pele, ho nka exemestane ho ka thusa ho thibela mofetše oa matsoele ho khutla.Ka kankere ea matsoele e tsoetseng pele lisele tsa mofetše li ka hola butle kapa tsa khaotsa ho hola ka botlalo.
Exemestane ke inhibitor ea aromatase.Sena se bolela hore e thibela enzyme ea aromatase (e fumanoang mesifa ea 'mele, letlalo, sefuba le mafura), e sebelisetsoang ho fetola li-androgens (lihomone tse hlahisoang ke litšoelesa tsa adrenal) hore e be estrogen.Ha estrogen e le sieo, lihlahala tse itšetlehileng ka homone ena bakeng sa ho hōla li tla fokotseha
Tšebeliso ea Exemestane(Aromasin).
1. Ke o mong oa metsoako e matla ka ho fetisisa e hatellang estrogen.
2. Ke e 'ngoe ea metsoako e molemo ka ho fetisisa ea ho fokotsa phello e nkhang hamonate ea steroids.
3. E fumaneha bakeng sa lihahi tsa 'mele tse nkang li-anabolic steroids.
4. E sebetsa ka ho thibela enzyme aromatase, ka mor'a moo e thibela tlhahiso ea estrogen.
5. Hape ke mofuta oa lisebelisoa tse tala tsa antineoplastic (hormonal).
Exemestane(Aromasin)Lisebelisoa
Aromasin e sebelisoa ho loantša mofetše oa matsoele le ho phahamisa testosterone 'meleng.
Exemestane acetate e thibela mokhoa oa ho nkha hamonate.Kahoo e theola tekanyo ea estrogen 'meleng.Ka kankere ea matsoele ea pele, ho nka exemestane acetate ho ka thusa ho thibela mofetše oa matsoele ho khutla.Ka kankere ea matsoele e tsoetseng pele lisele tsa mofetše li ka hola butle kapa tsa khaotsa ho hola ka botlalo.
Li-inhibitors tse ngata tsa aromatase ha se li-steroid ka sebōpeho leha e le sefe kapa sebopeho empa mona re tlameha ho etsa mokhelo.Utloisisa, ba bangata ba rekang Aromasin ba etsa joalo hobane tšebeliso ea eona le li-steroid tse ling hangata e ka ba ea bohlokoa haholo mabapi le litla-morao empa Aromasin ka boeona e na le litšobotsi tse ling tsa androgenic.Leha ho le joalo, ha re ntse re e-na le tlhaho ea androgenic ke ho fokotsa estrogen eo re amehileng haholo ka eona.
moloko oa boraro aromatase inhibitors, e sebelisoang kalafong ea mofetše oa matsoele o sa foleng le ho sebelisoa e le thuso kalafong ea mofetše oa pele oa matsoele.
Lik'hemik'hale tse ngata tsa matsoele li hlohlelletsoa ho hola ke lihomone tsa basali tsa estrogen le progesterone.Likankere tsena tsa matsoele li bitsoa "hormone sensitive" kapa "hormone receptor positive" 'me li ka phekoloa ka lithethefatsi tse thibelang liphello tsa lihomone tsena.
Ho basali ba bileng le nako ea ho ilela khoeli, estrogen e hlahisoa haholo-holo ka ho fetola li-androgens (lihomone tsa thobalano tse hlahisoang ke litšoelesa tsa adrenal) hore e be li-estrogen.Ts'ebetso ena e bitsoa aromatisation 'me e etsahala haholo-holo liseleng tse mafura, mesifa le letlalo.E hloka enzyme e itseng e bitsoang aromatase.
Aromasin e thibela tšebetso ea monko o monate.Kahoo e theola tekanyo ea estrogen 'meleng.Ka mofetše oa pele oa matsoele, ho nka Aromasin ho ka thusa ho emisa mofetše oa matsoele ho khutla.Ka kankere ea matsoele e tsoetseng pele lisele tsa mofetše li ka hola butle kapa tsa khaotsa ho hola ka botlalo.
