Metsoako e sebetsang ea Meriana Steroids Sarms CAS 595-33-5 Megestrol acetate
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Litaba tsa Motheo
Megestrol Acetateke mofuta oa letsoai oa acetate oa megestrol, motsoako oa maiketsetso oa progesterone ea tlhaho ea tlhaho ea basali e nang le ts'ebetso e ka bang anti-estrogenic le anti-antineoplastic.
Hangata e sebelisoa ho phekola bakuli ba nang le kankere ea matsoele ea metastatic.Ka kakaretso e mamelloa hantle, ntle le hore e ka baka boima bo sa rateheng.Ka mor'a moo, ho ile ha bontšoa hore megestrol acetate e hlahisa boima ba 'mele ho bakuli ba fapaneng ba kankere ea cachectic.
Ho fokotseha ho hoholo ha li-inserum tsa IL-1a le b, IL-2, IL-6, le TNF-o li ile tsa hlokomeloa ho bakuli ba kankere ba tšoaroang ka megestrol acetate e ka 'nang ea e-ba le mokhoa oa ho ntlafatsa takatso ea lijo le boima ba' mele. hore phello ke, bonyane ka karolo e 'ngoe, e kenelletsoeng ke NPY, e leng se susumetsang takatso ea lijo.
Tšebeliso
1. Megestrol acetate USP (Megace)E sebelisoa ho phekola Carcinoma ea letsoele kapa endorometrium.
2. Megestrol acetate (Megace), e leng semi-synthetic progestational steroid, ke ntho e sebetsang ka ho fetisisa e tsebahalang e susumetsang takatso ea lijo hona joale.Pele e ne e sebelisoa ho bakuli ba nang le mofetše le ba fumaneng immunodeficiency syndrome, ke lithuto tse seng kae feela tse kileng tsa nahana ka ho sebetsa ha moriana ona ho batho ba hōlileng ba sa fepehang hantle.
Megestrol acetate e na le thuso haeba anorexia e tebileng e le pontšo e ka sehloohong ea cachexia 'me haeba ho lebeletsoe ho phela ke libeke ho isa ho likhoeli.Megace e bontšitsoe ho eketsa takatso ea lijo haholo, empa eseng ho phela.Ho bakuli ba nang le nako e khuts'oane ea ho phela e boletsoeng esale pele, nako e khuts'oane ea corticosteroids e ka ba molemo ho tsosa takatso ea lijo le ho ba le litlamorao tse ntle ho ho nyekeloa ke pelo, bohloko le asthenia.
Tlhaloso e Akaretsang
17-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate(Megace), ke progestin e sebelisoang haholo-holo bakeng sa tsamaiso e fokolang ea kankere ea matsoele e tloaelehileng, e sa sebetseng, kapa ea metastatic endometrialor breast carcinoma.Megestrol acetate e boetse e bontšitsoe bakeng sa ho ntlafatsa takatso ea lijo ho bakuli ba AIDS.Motheo oa biochemical oa tšebeliso ena ea megestrol ha o hlake.
Tšebeliso ea ClinicalTs'ebetso ea progestin e ntlafatsoa hape ha tlamahano e habeli e hlahisoa lipakeng tsa maemo 6 le 7, joalo ka ha e fumanoa megestrol acetate.Megestrol e sebelisoa haholo-holo phekolong ea kankere ea matsoele le ea endometrial le ho basali ba postmenopausal ba nang le kankere e tsoetseng pele e itšetlehileng ka hormone.
Boemo ba PolokehoHo belaelloang hore ke kankere e nang le lintlha tsa liteko tsa carcinogenic le teratogenic.Chefo ka tsela ea methapo.Litlamorao tsa ho ikatisa ha motho bp le litsela tsa ho kengoa: litlamorao ho mae a bomme le lithapo tsa fallopian, liphetoho tsa potoloho ea ho ilela khoeli, le liphetoho tsa index ea basali.Litaba tsa phetoho li tlalehiloe.Liphello tsa teko ea ho ikatisa.Ha e futhumetse ho bola e ntsha mosi o bohale le mosi o hlabang.Setlhare sa FDA se sebelisoang ho phekola endometriosis le mofetše oa matsoele.A steroid.