Isteeroidka Anabolic-ka ee afka laga duro L-Triiodothyronine T3 Steroids Anabolic Steroids budada CasNO.55-06-1
T3 (Liothytonine Sodium) Faahfaahin degdeg ah
- L-Triiodothyronine (T3)
- Alias:3,3',5-Triiodo-L-thyroninesodiumsalt,Sodium(2S)-2-amino-3-[4- (4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl] propanoate
- daahirnimo: 99%
- Lambarka Diiwaangelinta CAS: 55-06-1
- Einecs No: 200-223-5
- MF: C15H11I3NNaO4
- MW: 672.96
Muuqashada: budo jaale ah oo cad ama khafiif ah, ku dhawaad aan dhadhamin.
- Fasalka : Darajada daawada
- Kaydinta: hadhka, ilaalinta xaddidan
- Isticmaalka : Waxay saamaysaa ku dhawaad habka nafsiga ah ee jidhka oo dhan, oo ay ku jiraan korriinka iyo korriinka, dheef-shiid kiimikaad, heerkulka jidhka, iyo garaaca wadnaha, sida, daaweynta xanuunada niyad-jabka iyo isticmaalka sida dheeraadka ah khasaaraha baruurta.
- T3 (Liothytonine Sodium)Codsiga
- Waxay saamaysaa ku dhawaad geedi socod kasta oo nafsiyeed ee jirka, oo ay ku jiraan koritaanka iyo horumarka, dheef-shiid kiimikaad, heerkulka jidhka, iyo garaaca wadnaha.T3 waxay kordhisaa heerka dheef-shiid kiimikaadka asalka ah, sidaas awgeed, waxay kordhisaa oksijiinta jidhka iyo isticmaalka tamarta.Heerarka dheef-shiid kiimikaadka aasaasiga ah waa shuruudaha kalooriga ugu yar ee loo baahan yahay si loo sii wado nolosha qofka nasanaya.T3 waxay ku shaqeysaa inta badan unugyada jirka, marka laga reebo dhowr jeer oo ay ku jiraan beeryarada iyo xiniinyaha.Waxay kordhisaa wax soo saarka Na +/K+ -ATPase iyo, guud ahaan, waxay kordhisaa isbeddelka macromolecules endogenous ee kala duwan iyadoo kordhinaysa isku-duubnidooda iyo hoos u dhac.
T3 (Liothytonine Sodium) Sharaxaada
Triiodothyronine, sidoo kale loo yaqaan T3, waa hoormoonka tayroodh.Waxay saamaysaa ku dhawaad habsocod kasta oo nafsiyeed oo jidhka ah, oo ay ku jiraan koritaanka iyo horumarka, dheef-shiid kiimikaadka, heerkulka jidhka, iyo garaaca wadnaha.
Wax soo saarka T3 iyo prohormone tyroxine (T4) waxaa dhaqaajiya hoormoonka tayroodh-kicinta (TSH), kaas oo laga sii daayo qanjirka pituitary.Dariiqan waxaa lagu maamulaa habka jawaab celinta-loop-ka-xiran: Heerarka sare ee T3, iyo T4 ee balasmaha dhiigga ayaa xannibaya soo saarista TSH ee qanjirka pituitary ee.Maaddaama xaddiga hormoonnadani ay hoos u dhacaan, qanjirka pituitary wuxuu kordhiyaa wax soo saarka TSH, iyo hababkaas, habka xakamaynta jawaab-celinta ayaa loo sameeyay si loo xakameeyo qadarka hormoonnada tayroodhka ee ku jira dhiigga.
Sida hormoonka dhabta ah, saamaynta T3 ee unugyada bartilmaameedka ah ayaa qiyaas ahaan afar jeer ka xoog badan kuwa T4. Hormoonka tayroodhka ee la soo saaro, kaliya 20% waa T3, halka 80% loo soo saaro T4.Qiyaastii 85% T3 wareegeysa ayaa markii danbe lagu sameeyay tayroodhka iyadoo laga saarayo atamka iodine-ka ee kaarboon atamka lambarka shanaad ee giraanta dibadda ee T4.Si kastaba ha ahaatee, xoojinta T3 ee balasmaha dhiigga bini'aadamka waxay ku saabsan tahay hal-40th ee T4.Tan waxaa lagu arkay xaqiiqda sababtoo ah nolosha nuska gaaban ee T3, taas oo ah maalmo 2.5 kaliya. Tani waxay la mid tahay nolosha nuska ah ee T4, oo ku saabsan 6.5 maalmood.
COA:
Shayga | Tilmaamid | Natiijo | |
Muuqashada | Budo midab leh oo aan ur lahayn, ku dhawaad cad ama buff | dhaaf | |
Solubility | 1,Aad u yara milmi biyaha | dhaaf | |
2,wax yar oo khamriga ku milma | dhaaf | ||
3,dhab ahaan aan milmi karin inta badan dareerayaasha kale ee organic | dhaaf | ||
4, waxay ku milmaysaa xalalka sodium hydroxide aqueous aqueous | Gudub | ||
Aqoonsiga | a) Kuleyl ku saabsan 50 mg oo leh dhowr dhibcood oo sulfuric acid ah oo ku jira kareemka dhoobada ah: uumiga violet ee iodine ayaa la sameeyay. | dhaaf | |
b) Wakhtiga haynta ee ugu sarraysa waxa loo xaqiijiyaa RS | dhaaf | ||
Khasaare xagga qalajinta | In aan ka badnayn 4.0% | 0.46% | |
[a]20/D C=1 gudaha 1M HCl/EtOH 1:4 | +18 ~ +22o | 20.9o | |
Assay (HPLC) | Aan ka yarayn 95.0% | 99.18% | |
Levothyroxine sodium | In aan ka badnayn 5.0% | 0.68% | |
Gabagabo: | Ilaa heerka Dhoofinta |