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Dhirta dabiiciga ah waxay soo saartaa CAS 51-34-3 Scopolamine

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  • Magaca guud:Scopolamine
  • Lambarka CAS:51-34-3
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    Macluumaadka aasaasiga ah

    51-34-3

    Scopolamine(hyoscine) waxaa laga helaa xubno kala duwan oo Solanaceae ah (tusaale, H. niger, Duboisia myoporoides, Scopolia spp., iyo Datura metel).Scopolamine inta badan waa ka go'doonsan tahay khamriga hooyada ee ka haray go'doominta hyoscyamine.

    Hyoscine waa magaca da'da weyn ee alkaloidkan, in kasta oo scopolamine uu yahay magaca la aqbalay ee Maraykanka. Scopolamine waa qaybta levo ee isku dhafka jinsiyadeed ee loo yaqaan atroscine.Alkalood-ka ayaa si tartiib tartiib ah loogu diyaariyaa joogitaanka alkali-la'aanta.

    Alkaloodku wuxuu ku dhacaa qaabka levorotatory, viscousliquid kaas oo wax yar ku milmay biyaha laakiin khamriga aad u milma, chloroform, ama ether.Waxay samaysaa cusbo crystalline leh asiidhyada intooda badan, iyadoo hydrobromide uu yahay kan ugu xasiloon iyo kan ugu caansan ee la aqbalo.Xalka biyaha leh ee hydrobromide oo ka kooban 10% mannitol ayaa la sheegay inuu u nugul yahay burburka marka loo eego xalalka aan la ilaalin.

    Farmashiistaha

    Scopolamine butylbromide, scopolamine wax laga beddelay, waa daawada ka hortagga choline ee durugsan;Ma aha oo kaliya inay simi karaan murqaha muruqyada laakiin sidoo kale waxay xannibi karaan ganglion iyo isgoyska neuromuscular waxayna saameyn daciif ah ku leedahay xarunta.Daroogadu waxay leedahay saameyn xooggan oo ku saabsan muruqyada siman ee mindhicirka marka loo eego atropine iyo anisodamine;waxay si door ah u yareyn kartaa mareenka caloosha iyo mindhicirka, mareenka biliary, iyo kaadi mareenka si siman muruqa muruqa waxayna ka hortagtaa peristalsiskeeda.

    Scopolamine butylbromide waxay ku leedahay saameyn yar oo ku saabsan wadnaha, ardayga, iyo qanjidhada salivary, sidaas darteed marar dhif ah ayay keentaa dareenka dhexe ee dareenka, kala-baxa, joojinta dheecaanka candhuufta, iyo falcelinta kale ee xun, taas oo ka duwan atropine.

    Scopolamine butylbromide waa antagonist of M cholinergic reseptor, saamayn farmaajo la mid ah atropine, laakiin waxa ay leedahay sifooyin u gaar ah oo faa'iido cad in hagaajinta microcirculation dhiigga.

    CAS 94-15-5
    Levamisole
    Levamisole

    Isticmaalka

    1. ScopolamineWaxaa loo isticmaalaa ficil ahaan calaamado la mid ah sida atropine, laakiin waa in la ogaadaa in ay saameyn ku yeelato dhaqdhaqaaqa dhaqdhaqaaqa, waxaana lagu talinayaa in lagu daaweeyo calaamadaha Parkinsonian.

    2. cholinergic (ophthalmic).


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