Nafarelin CAS: 76932-56-4 RS-94991-298 Nasanyl

Nafarelin, oo lagu iibiyo magacyo ganacsi sida Synarel, waa gonadotropin sii daaya hormoonka agonist (GnRH agonist) daroogada loo isticmaalo in lagu daweeyo endometriosis iyo baaluqnimada hore.Waxa kale oo loo isticmaalaa in lagu daweeyo fibroids uterineine, la xakameeyo kicinta ugxan-sidaha inta lagu jiro bacriminta vitro (IVF), iyo iyada oo qayb ka ah daawaynta hoormoonka iskutallaabta.Daawada waxaa loo isticmaalaa buufin sanka ah laba ilaa saddex jeer maalintii.

Dhibaatooyinka soo raaca ee nafarelin waxay la xiriiraan yaraanta hoormoonka jinsiga waxaana ka mid ah calaamadaha heerarka testosterone hooseeya iyo heerarka estrogen ee hooseeya, sida iftiinka kulul, cilladda galmada, atrophy siilka, iyo lafo-beelka.Nafarelin waa gonadotropin-sii-daynta hormoonka agonist (GnRH agonist) kaas oo ka shaqeeya ka hortagga gonads inay soo saaraan hormoonnada galmada.Waxay hoos u dhigi kartaa heerarka hoormoonka galmada ee labada jinsi 95 boqolkiiba.Nafarelin waa peptide oo ah analoogga GnRH.

Nafarelin waxaa loo soo bandhigay isticmaalka caafimaadka 1990. Waxaa si weyn looga isticmaalaa adduunka oo dhan, sida Waqooyiga Ameerika, Yurub, iyo meelo kale oo adduunka ah.Daawadu waa mid ka mid ah labada analogues ee GnRH ee dawo ahaan loo isticmaalo sida buufin sanka ah, kan kalena waa Bucherelin

Isticmaalka caafimaadka:
Nafarelin waxa loo oggolaaday in lagu daweeyo endometriosis iyo baaluqnimada hore.Waxa kale oo loo isticmaalaa in lagu daweeyo fibroids uterineine.Daawada waxaa loo isticmaalaa in lagu xakameeyo kicinta ugxan-sidaha inta lagu jiro bacriminta vitro (IVF).Nafarelin waxaa loo isticmaalaa sidii xannibaadda baaluqnimada dhalinyarada transgender iyo in la xakameeyo heerarka testosterone ee haweenka transgender.Nafarelin waxa kale oo loo isticmaali karaa in lagu daweeyo hypertrichosis iyo polycystic ovary syndrome iyada oo la dhimayo gonadotropin iyo heerarka androgen.Waxay wax ku ool u tahay daaweynta hyperplasia qanjirka 'prostatic'