Larazotide acetate CAS 881851-50-9
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Sifada:
| magac guud | Larazotide acetate | Magaca Ingiriisiga | Larazotide acetate |
|---|---|---|---|
| Lambarka CAS | 881851-50-9 | miisaanka kelli | 785.88500 |
| caanaha molecular | C34H59N9O12 |
|---|
| tiro sax ah | 785.42800 |
|---|---|
| PSA | 360.55000 |
| LogP | 3.73650 |
Isticmaalka:
Larazotide acetate waa daawada xakamaynta isku-xidhka xiidmaha, oo hore loo yaqaan Innovate Biopharmaceuticals ka hor inta aan la isku darin, taas oo hadda lagu tijaabiyo bukaanada qaangaarka ah ee qaba cudurka baruurta ee wajiga III ee tijaabada caafimaadka.peptide-kan hal silsilad ah ayaa laga soo qaatay zonulin bini'aadan ah, oo ah modulator caan ah oo isku xidhid adag leh kaas oo kor u qaaday muujinta unugyada mindhicirka ee bukaanka qaba cudurka baruurta.LA waxa kale oo ay la wadaagtaa qaabdhismeed la mid ah Vibrio cholerae zonula occludens toxin (Zot), kaas oo ah enterotoxin kaas oo carqaladeeya qaabdhismeedka isku-xidhka cidhiidhiga ah ee dhex-dhexaadka ah iyada oo loo marayo actin polymerization iyo isbeddellada cytoskeletal taas oo keenta kororka mindhicirka mindhicirka iyada oo loo marayo calaamadaynta gudaha.Inkasta oo LA ay muujisay ballanqaad ku saabsan tijaabooyinka bukaan-socodka ee bukaannada qaba cudurka baruurta, daraasadihii ugu dambeeyay ee isticmaalaya noocyada dhaawacyada xayawaanka ee kala duwan waxay muujinayaan isticmaalka suurtagalka ah ee LA ee cudurrada kale sababtoo ah awoodda ay u leedahay inay maamusho isku-xirnaanta adag.Dib-u-eegid-yar-yar ayaa ujeeddadeedu tahay inay bixiso il faahfaahsan oo macluumaadka hadda ah ee octapeptide-kan.
