JWH18 Jwh18 5cl Sgt78 7A 7ad Adb S709 CAS 209414-07-3
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Isticmaalka
JWH-018 (1-pentyl-3- (1-naphthoyl) indole, NA-PIMO ama AM-678) waa kiimiko xanuunka xanuunka ee qoyska naphthoyl indole, kaas oo lagu muujiyay CB 1 iyo CB 2 cannabinoid reseptors, Waxay leedahay qaar ka mid ah xulashada CB 2. Waxay soo saartaa saamaynta xayawaanka la midka ah THC, cannabinoid si dabiici ah laga helo xashiishadda, taasoo horseedaysa isticmaalka alaabada xashiishadda synthetic, taas oo wadamada qaarkood si sharci ah loogu iibiyo "isku-darka udgoonka."
Sida agonist dhamaystiran oo loogu talagalay CB 1 iyo CB 2 cannabinoid reseptors, xaruntan waxaa loo kala saaraa xanuunka xanuunka.Saamaynta xanuunka ee cannabinoid ligands oo ay dhexdhexaadiyaan CB1 reseptors ayaa si fiican loogu muujiyay daaweynta xanuunka neuropathic, xanuunka kansarka, iyo arthritis.
Iskudhisyadani waxay ku shaqeeyaan iyaga oo la jaan qaadaya hormoonnada endocannabinoid ee jirka si dabiici ah u dhaca, sida 2-AG iyo anandamide (AEA), kuwaas oo bayooloji ahaan firfircoon oo xoojin kara ama joojin kara calaamadaha dareemayaasha.Sababtoo ah wax yar ayaa laga ogyahay sababaha xanuunka daba-dheeraada, cilmi baaris iyo horumarin dheeraad ah waa in la sameeyaa ka hor inta aan la xaqiijin awoodda daaweynta ee xeryahooda bayoolojiga ah.
Tilmaamaha
Lambarka CAS | 29622-29-5 | Magaca guud | RAD 150 |
Dxasadnimo | 1.088g/cm3 | Bbarta saliidda | 424.5ºC at 760mmHg |
Mcaanaha olecular | C16H25ClN2Ama | Mmiisaanka olecular | 296.83600 |
PSA | 35.83000 | Fbarta lagu dhufto | 210.5ºC |