Epithalon CAS: 307297-39-8 EpithalonAcetate Glycine 55 borotiin la sheegay
Isticmaalka
Daraasad in vivo ah oo ku saabsan jiirarka gabowga ayaa lagu ogaaday in daawaynta epitalon ay si weyn u yaraysay dhacdooyinka koromosoomyada aberrations ee jiirarka nooca duurjoogta ah iyo jiirarka oo lagu garto phenotype gabowga degdega ah, kaas oo la jaan qaadaya kororka dhererka telomere.
Daraasad kale oo lagu sameeyay jiirka gabowga ayaa lagu ogaaday in epitalon uu kordhay waxqabadka antioxidant enzymes superoxide dismutase, glutathione peroxidase, iyo glutathione -S-transferase.
Tijaabooyin lagu sameeyay dheddig C3H/He jiirar hal sano jir ah, Epitalon waxay hoos u dhigtay tirada burooyinka iskood u dhaca iyo tirada metastases ee jiirarka kuwaas oo soo saaray burooyinka iskood u dhaca, waxaana la qiyaasayaa inay leeyihiin burooyinka xakameynaya iyo guryaha ka hortagga metastatic.
Daraasad ku saabsan digaagga oo maraya pituitectomy dhallaanka iyo korriinka xiga, epitalon wuxuu kor u qaaday dib u soo kabashada qaab-dhismeedka morphological ee thymus, iyo sidoo kale qaabka iyo shaqada qanjidhada thyroid.
Epitalon waxay u muuqataa inay kordhiso kororka lymphocyte ee thymus, malaha kordhinta gamma interferon ee ay soo saaraan unugyada T.
Daraasad kale oo lagu sameeyay jiirarka da'da weyn ayaa muujisay in iftiinka joogtada ah, ama nidaamka iftiinka dabiiciga ah ee gobollada waqooyi, uu kordhay nolosha jiirarka.
