Shiinaha ayaa bixiya Lidocaine CAS 137-58-6 oo leh Qiimaha ugu Wanaagsan
Macluumaadka aasaasiga ah
ku milma ethanol, ether, benzene, chloroform iyo saliid, oo aan lagu milmi karin biyaha.Sida caadiga ah loo isticmaalo hydrochloride salka, lidocaine hydrochloride (C14H22N2O·HCl, [73-78-9]) waa budo crystalline cad.Meesha dhalaalidu waa 127-129 ℃, halka barta dhalaalka ee monohydrate ay tahay 77-78℃.Aad ugu milmay biyaha, 0.5% aqueous pHO4.0-5.5.ur aan ur lahayn, dhadhan hemp qadhaadh.
Isticmaalka
Alaabta ayaa ah suuxinta gudaha amide.Waxaa si weyn loogu isticmaalaa suuxinta dusha sare, suuxinta gudaha, suuxinta kaadida iyo suuxdinta epidural'ka.LD50 ee lidocaine hydrochloride waxay ahayd 290mg/kg.
Codsiyada kiliinikada waxaa ka mid ah suuxinta gudaha, suuxdinta epidURAL, suuxinta jirka (oo ay ku jiraan suuxinta xuubka xuubka thoracoscopy ama qaliinka caloosha), iyo xannibaadda dareemayaasha.Epinephrine waxaa lagu dari karaa daawada suuxinta si loo dheereeyo waqtiga suuxinta oo loo yareeyo waxyeelada sida ku-sumowga lidocaine.
Lidocaine waxa kale oo loo isticmaali karaa in lagu daweeyo arrhythmias ventricular ka dib wadnaxanuun myocardial ba'an, oo ay ku jiraan foosha ventricular hore, tachycardia ventricular, ventricular arrhythmias ay keento sumowga digitalis, qalliinka wadnaha iyo catheterization wadnaha, oo ay ku jiraan foosha hore ee wadnaha, tachycardia ventricular.Waxa kale oo loo isticmaalaa bukaanada qaba xaalad suuxdineed kuwaas oo aan ka jawaabin anticonvulsants kale iyo suuxinta maxaliga ah ama intraspinal.Caadiyan waxtar uma laha arrhythmias supraventricular.
Tilmaamaha
| Magaca Alaabta | Lidocaine |
| CAS | 137-58-6 |
| MF | C14H22N2O |
| MW | 234.34 |
| EINECS | 205-302-8 |
| barta dhalaalaysa | 66-69°C |
| Barta karkarinta | bp4 180-182 °;bp2 159-160° |
| cufnaanta | 0.9944 (qiyaasta adag) |
| index refractive | 1.5110 (qiyaas) |
| Fp | 9℃ |
| heerkulka kaydinta. | Ku kaydi RT |
| milmayn | ethanol: 4 mg/ml |
| pka | pKa 7.88 (H2O) (Qiyaas) |
| qaab | budo |
| midab | Cadaan ilaa waxoogaa huruud ah |
| Biyuhu milmayn | ficil ahaan aan la xalin karin |
| Merck | 14,5482 |
| Xasilooni | DegganAan ku habboonayn walxaha oksaydhaynta ee xooggan. |
| InChiKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| Tixraaca XogtaBase ee CAS | 137-58-6 (Tixraaca Xogta Saldhigga CAS) |