Dawooyinka Kaaliyaha ah ee Qalabka Kiimikada CAS 59-46-1 PROCAINE
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Macluumaadka aasaasiga ah
Sharaxaada
Procaine waa suuxdin maxalli ah oo leh shaqeyn para-amino.Dareen-celinta waxay inta badan khusaysaa caafimaadka, caafimaadka ilkaha iyo xirfadaha caafimaadka xoolaha.
Guryaha Kiimikada
Cusbada hydrochloride ee 2- (diethylamino) ethyl p-aminobenzoate (C13H21ClN2O2 ama N2C6H4COOCH2CH2NH(C2H5)2HCl) ayaa guud ahaan loo yaqaan procaine.Inkasta oo ester-ka PABA uusan ku milmi karin biyaha, cusbada hydrochloride aad bay ugu milmi kartaa biyaha.
Adeegsada
1.Procaine (Novocain) waxaa inta badan loo isticmaalaa daaweynta ilkaha ama hababka daawaynta u baahan suuxdin galinta, xannibaad durugsan, ama xannibaad laf dhabarta.
2.xakameeyaha kanaalka sodium
3. Procaine waa kanaalka soodiyamka xannibaya iyo xannibaadaha hababka kala duwan.
Isticmaalka
Isticmaalka CaafimaadProcaine si dhakhso ah ayey u metabolized plasma by cholinesterases iyo beerka iyada oo loo marayo ester hydrolysis by a pseudocholinesterase.Nolosha nuska ah ee vitroelimination waa qiyaastii 60 ilbiriqsi.Xaalad kasta oo hoos u dhigta xoogga cholinesterase waxay kordhin kartaa soo-gaadhista procaine iyo sunta suurtagalka ah.Dhaqdhaqaaqa Decreasedenzyme waxaa laga heli karaa yaraanta hidde-sideyaasha, beerka-cudurka, malignant, nafaqo-xumo, kelyo-xumo, gubasho, saddexda bilood ee uurka, iyo ka dib qalliinka wadnaha sambabada.Ester hydrolysis waxay soo saartaa PABA, isku dhafka ka mas'uulka ah falcelinta xasaasiyadda ee caadiga ah ee suuxinta tayeerka.Procaine looma isticmaalo dusha sare sababtoo ah awood u la'aanta inay ka gudubto xuubka dufanka waxayna ogaataa in loo isticmaalo sida wakiilka ka hortagga maqaarka ama xuubka xuubka, hababka gaaban.Procaine waxa kale oo loo isticmaalaa dareemaha dareemaha ee durugsan iyo sidii wakiilka epidural si loo ogaado cilladaha xanuunka.