Walxaha Dawooyinka Firfircoon ee Steroids Sarms CAS 595-33-5 Megestrol acetate
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Macluumaadka aasaasiga ah
Megestrol Acetatewaa qaabka cusbada acetate ee megestrol, oo ka soo jeeda dabiiciga ah ee hormoonka jinsiga dumarka ee dabiiciga ah ee progesterone oo leh firfircoonida anti-estrogenic iyo antineoplastic.
Waxaa inta badan loo isticmaalaa daawaynta bukaanada qaba kansarka naasaha ee metastatic.Guud ahaan si fiican ayaa loo dulqaatay, marka laga reebo inay keeni karto miisaan korodh aan loo baahnayn.Ka dib, waxaa la muujiyay in megestrol acetate ay soo saartay miisaan korodhka bukaannada kansarka cachectic ee kala duwan.
Heerarka inserum hoos u dhigista ee IL-1a iyo b, IL-2, IL-6, iyo TNF-o ayaa lagu arkay bukaanada kansarka lagu daaweeyay megestrol acetate taas oo laga yaabo inay xamili karto habka rabitaanka cuntada iyo korodhka miisaanka jidhka. in saamaynta ay tahay, ugu yaraan qayb ahaan, ay dhexdhexaadinayso NPY, oo ah kicinta rabitaanka cuntada ee dhexe.
Isticmaalka
1. Megestrol acetate USP (Megace)Waxaa loo isticmaalaa in lagu daaweeyo Kansarka naaska ama endorometrium.
2. Megestrol acetate (Megace), steroid progestational semi-synthetic, waa kicinta rabitaanka cuntada ee ugu waxtarka badan ee loo yaqaan waqtigan.Markii hore loogu isticmaali jiray bukaannada qaba kansarka iyo cilladda difaaca jirka, kaliya dhowr daraasadood ayaa tixgeliyey ku habboonaanta dawadan dadka da'da ah ee nafaqo-xumada hayso.
Megestrol acetate waa faa'iido leh haddii anorexia qoto dheer ay tahay muujinta ugu weyn ee cachexia iyo haddii badbaadada la filayo waa toddobaadyo ilaa bilo.Megace ayaa la muujiyay inay si weyn u kordhiso rabitaanka cuntada, laakiin maaha badbaadada.Bukaanka leh badbaado la saadaaliyay oo gaaban, koorsada corticosteroids ayaa faa'iido u yeelan karta kicinta rabitaanka cuntada oo ay saameyn togan ku yeelato lallabbo, xanuun, iyo asthenia.
Sharaxaada Guud
17-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate(Megace), waa progestin marka hore loo isticmaalo maaraynta palliative ee kansarka naasaha ee soo noqnoqda, aan shaqaynayn, ama metastatic endometrialor naasaha.Megestrol acetate ayaa sidoo kale loo tilmaamay kor u qaadida rabitaanka cuntada ee bukaanada qaba AIDS-ka. Saldhigga bayoloji ee isticmaalka megestrol ma cadda.
Isticmaalka CaafimaadDhaqdhaqaaqa Progestin waa la sii wanaajiyey marka isku-xidhka labanlaab ah lagu soo bandhigo inta u dhaxaysa boosaska 6 iyo 7, sida laga helo megestrol acetate.Megestrol waxa loo isticmaalaa daawaynta kansarka naasaha iyo endometrial iyo dumarka postmenopausal ee qaba kansarka hormoonka ku tiirsan ee horumarsan.
Xogta BadbaadadaKansarka looga shakisan yahay ee leh baaritaanka kansarka naasaha iyo xogta teratogenic.Sunta marinka xididada.Saamaynta taranka bani'aadamka ee xiidmaha bp iyo dariiqyada la geliyo: saamaynta ugxan-sidaha iyo tuubooyinka ugxan-sidaha, isbeddelka wareegga caadada, isbeddellada tusmada bacriminta dumarka.Xogta is beddelka ayaa la sheegay.Saamaynta taranka ee tijaabada ah.Marka loo kululeeyo si uu u burburo waxay soo daysaa qiiq qallafsan iyo qiiq xanaaq badan.Daawo iska leh FDA oo loo isticmaalo daawaynta endometriosis iyo kansarka naasaha.steroid ah