Musoro wekurwisa kuchembera wakawedzera kufarirwa mumakore achangopfuura, nezvidzidzo zvakasiyana-siyana zvichibuda zvisingaperi.
Nguva nenguva, rimwe boka rekutsvagisa rinowana chinhu chinorwisa kuchembera chinogona kutibatsira kurarama kusvika makore zana.
Isu vanhu tine muganhu weupenyu hwemakore zana nemakumi mashanu, nekuti matelomere anopfupisa zvishoma pamakore maviri kusvika matatu ega ega, uye masero anogona kupatsanura kanenge ka50, anodaro Hafrick wetelomere Theory.
Kune zvakare dzimwe nyanzvi dzine tariro dzinoti: munhu wekutanga kurarama kusvika kumakore 1000, akazvarwa, munyika yedu, angave iwe oh.
Nekuvandudzwa kwebiomolecular biology, rimwe zuva tinogona kuwana mashiripiti ayo achatibatsira kurarama kwenguva refu.
Saka, rarama uine hutano, shanda nesimba kuti uite mari, uye mirira tekinoroji kukura rimwe zuva, pamwe, unogona chaizvo kurarama hupenyu hurefu.
Nhasi, ndiri kukuzivisai kune mamwe anonyanya kuvimbisa ekudzivirira kuchembera ayo anozivikanwa, uye tarisa zvishoma zvawaona.
1. Epitalon
Epitalon is synthetic anti-aging peptide, inogadzirwa kubva kune amino acid chain alanine-glutamine-asparagine-glycine, iyo inosimudzira telomerase basa mumuviri kubatsira kuderedza chiyero chekuchembera.
Matelomere akafanana neheti dzakaoma dzinodzivirira DNA.Makromosome akawanda mumuviri ane matelomere kumativi ose maviri;Basa guru retelomerase nderokubatsira kuchengetedza kureba kwematelomeres mumuviri.
Zvimwe zvirwere zvinosanganiswa nema telomere mapfupi, zvichiita kuti kukurumidza kukwegura;Epitalon inogona kushandiswa kurapa zvirwere zvinokonzera kukwegura kusati kwasvika, zvakadai seBloom syndrome uye Werner syndrome.
Epitalon inobatsirawo kuderedza njodzi yezvirwere zvine chekuita nekushomeka kwetelomerase, senge chirwere cheshuga, nekuti insulin secretion inodzivirirwa nekushomeka kwetelomerase.
Iyo peptide inogonawo kuva nemigumisiro yakanaka pahutano hwemwoyo uye inogona kubatsira kudzivirira chirwere chemwoyo;Vesainzi vari kudzidza kugona kwayo mukurapa mapundu.
2: Curcumin
Turmeric inonyanya kushandiswa kwechikafu cheIndia, uye curcumin ndiyo inonyanya kudzidzwa inoshandiswa mu turmeric, ine yakasimba anti-inflammatory uye antioxidant properties.
Zvidzidzo zvakaratidza kuti curcumin activate sirtuins (deacetylases) uye AMPK(AMP-activated protein kinase), iyo inobatsira kunonoka kuchembera kwesero uye kurebesa hupenyu.
Mukuwedzera, curcumin yakaratidzwa kurwisa kukanganisa kwesero uye zvakanyanya kuwedzera hupenyu hwenhunzi dzemichero, roundworms, uye mice;Inogonawo kunonoka kutanga kwezvirwere zvine chokuita nezera uye kuderedza zviratidzo zvezvirwere zvine chokuita nezera
3: cannabinoid
Iwo anoshanda makomisheni e cannabis, anozivikanwa pamwe chete se cannabinoids, iboka re terpenoid phenolic komisheni, iyo inonyanya kuzivikanwa iyo tetrahydrocannabinol (THC) uye cannabidiol (CBD).
CBD inogona kurwisa mahara radicals mumasero eganda, ichiita se antioxidant uye anti-kukwegura mumiriri.Inowanzowedzerwa kune zvigadzirwa zvekuchengetedza ganda uye inowanzoshandiswa kugadzirisa kurwadziwa kusingaperi, nemigumisiro yakanaka
4: spermidine
Spermidine inhengo yechisikigo yembeu, uye miviri yedu (yose murume nemukadzi) inongoburitsa chikamu chetatu chayo, neimwe yese ichiuya kubva mukudya kwedu.
Zvokudya zvaro zvinosanganisira: chembere chizi, howa, natto, mhiripiri, gorosi germ, cauliflower, broccoli, nezvimwe.
Vanhu vekuAsia vane mazinga epamusoro earginous acid mukudya kwavo, izvo zvingave zvine chekuita nehupenyu hwavo hurefu.
Tsvagiridzo ye spermidine yanga ichikura mumakore achangopfuura, uye yakawanikwa iine zvinotevera mhedzisiro:
Wedzera hupenyu hurefu hwehupenyu;
Kuvandudza ruzivo rwekuziva kwevakwegura;
Neuroprotective effect;
Kuderedza kufa kwezvikonzero zvese;
Kuderera kweropa;
Kukurudzira autophagy uye kunonoka senescence;
Inoita kuti bvudzi rikure nekukurumidza uye nzara dzisimbe.
5: ketone muviri
Chimwe chezvikonzero zvakakosha kudya kwe ketogenic kwakakurumbira kurasikirwa nekurema uye kujeka kwepfungwa.
Apo muviri unotanga kupisa mafuta emuviri, unobudisa miviri ye ketone, iyo inopa simba rakachena kuuropi uye inovandudza kushanda kwayo.
Ketoni dzine zvinhu zvinopesana nekukwegura, uye zvidzidzo zvakawana kuti BHB (beta-hydroxybutyric acid) inogona kukurudzira kupatsanurwa kwesero, kudzivirira kukwegura kwemasero, uye kuchengetedza mitsipa yeropa uye uropi huduku.
Muviri unogona kugadzira miviri ye keto nekudzivisa macarbohydrates, kana kuti inogona kutora exogenous keto supplements kuti ikurumidze kuita uye kuderedza marwadzo ekuchinja, inozivikanwa se "keto flu."
Zvokudya zveKetogenic, kana kutora exogenous keto supplements, zvinogona kunonoka kuchembera, kuvandudza mashandiro enjere, uye kubatsira kudzivirira zvirwere zveurourodegenerative seAlzheimer's.
6: Dasatinib
Sezvatinokura, mamwe masero edu anonzvenga immune system.Aya masero "asara" haaite zvaaifanira kuita, asi anopisa simba.
Masero akadaro "zvekudya uye pasina basa", anozivikanwawo se "zombie masero", kana maseru maseru, anounganidza nekufamba kwenguva, zvichiita kuti muviri ushande zvishoma.
Kutsanya, maekisesaizi uye mamwe mararamiro ane hutano anotanga autophagy, iyo inochenesa zombie masero.
Dasatinib, mushonga wechemotherapy unoshandiswa mukurapa leukemia, unogonawo kubvisa zvinobudirira masero emafuta ekuchembera uye kuderedza kuvanzika kwepro-inflammatory cytokines mumuviri weadipose tissue.
Ndiwo mushonga wekutanga weSenolytics kuwanikwa, mushonga unosarudza kuchenesa maseru maseru nekuvhiringidza nzira dzinoratidza senescent cell, kudzima SCaps (anti-apoptotic pathways).
Zvinhu zvinogona kubvisa masellcelles anosanganisira PCC1 kubva kuChinese Academy of Sciences, pamwe chete nezvimwe zvinongedzo zvakaita sequercetin.
Nguva yekutumira: Feb-24-2023