Manufacture supply Dihexa CAS 1401708-83-5

Kushandisa:

DIHEXA (PNB-0408), oligoplase reagent, inonzi IV analog yevascular tensionin IV ine basa remuromo uye ropa-brain barriers permeability.Dihexa high-friendly uye simba rinobatanidza hepatocyte growth factor (HGF), ChemicalBookkd value is 65PM, uye inowedzera basa rayo kune receptor C-MET.Dihexa inoratidza yakanakisa anti-ejaculation chiitiko uye inovandudza yekuziva mabasa mumhando dzemhuka.Dihexa ine mukana wekudzidza chirwere cheAlzheimer.

Dihexa inosunga nehupamhi hwepamusoro kuHGF uye zvose dihexa uye mubereki wayo musanganiswa Norleucine 1-AngIV induce c-Met phosphorylation pamberi pe subthreshold concentrations yeHGF uye kuwedzera HGF-inotsamira kupararira kwesero.Kupfuurirazve, dihexa uye Nle1-AngIV inokurudzira hippocampal spinogenesis uye synaptogenesis yakafanana neHGF pachayo.Dihexa inonyatso inhibits HGF dimerization pa 1 μM. Nepo dihexa pa 1 nM uye 10 pM chete isingaite c-Met, inonyatso wedzera huwandu hweHGF pa 1.25 uye 2.5 ng / mL kuti iite c-Met.

Dihexa ine nguva yakareba inotenderera hafu yeupenyu.Dihexa inoratidza kuita kwekuziva.Inovandudza kudzidza kwenzvimbo mumakonzo akura.Dihexa induces spinogenesis mune yakasimwa hippocampal neurons.