Human Choroinic Gonadotrophin HCG CAS:9002-61-3
Usage
Human chorionic gonadotropin (hCG) ihomoni yeglycoprotein inovanzwa neiyo placental endodermal masero.Basa rayo guru nderokukurudzira corpus luteum, iyo inobatsira kuenderera mberi kweesrogen uye progesterone, kuitira kuti ikurudzire kuumbwa kwechibereko chekudzivirira uye kuita kuti placenta ikure uye iwedzere.Pakangoiswa embryo, masero eblastoderm anotanga kuburitsa hCG, saka kubata pamuviri kunogona kutariswa nemazinga ehCG muropa kana weti.
Yakanga yakagadzirwa ne244 amino acid zvakasara, ine molecular uremu hwe36.7kDa uye saizi ye7.5 × 3.5 × 3 nm.Iyo heterodimer ine imwechete α subunit se luteinizing hormone (LH), follicle-stimulating hormone (FSH) uye thyrotropin (TSH), asi yakasiyana β subunit.Iyo α subunit yaive ne92 amino acid zvisaririra, uye iyo β subunit yaive ne145 amino acid masara.
HCG synthesis muvakadzi inowedzera zvakanyanya mushure mekubata pamuviri, uye kuvapo kwehCG mu plasma uye urini ndeimwe yezviratidzo zvekutanga zvepamuviri uye inoshandiswa pakuongorora pamuviri.
(1) Iine basa reFSH neLH kuchengetedza hupenyu hwekuenda kumwedzi corpus luteum uye kuita kumwedzi corpus luteum ive gestational corpus luteum;
(2) Kurudzira kunhuhwirira kwe androgens muestrogen, uye kukurudzira kuumbwa kweprogesterone;
(3) Kudzivisa kukurudzirwa kwechirimwa lectin pane lymphocytes, chorionic gonadotropin yevanhu inogona kushambadzirwa pamusoro pemasero etrophoblast, kuitira kuti kudzivirira kurwiswa kwemasero embryonic trophoblast ne lymphocytes yaamai;
(4) LH basa, pamberi pepituitary isati yabudisa LH, inokurudzira fetal testis kuti ibudise testosterone kukurudzira kusiyana kwepabonde kwevarume;Inogonawo kukurudzira kukura kwegonadal, murume anogona kukurudzira simba re testis mesenchymal masero, kuwedzera kuburitswa kwehomoni yechirume (testosterone).Izvo zvakakosha zvikuru pakurapa kwevarwere vechirume vane pituitary joint defects, izvo zvisingagone chete kukurudzira kukura kwegonad uye echirume secretion yehomoni, asi zvakare kukurudzira kuvandudzwa kwehunhu hwechipiri hwepabonde.
(5) Inogona kusunga kune TSH receptor yemasero ehutano hwemadzimai uye inokurudzira utachiona hwekuita.
2.Ndeipi yekurongedza yaunoshandisa kutumira zvigadzirwa zvako?
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3.Ndeipi yakajairika nguva yekutungamira?
4.Ndeipi mazwi ako ekutumira?
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5.Ko fekitari yako inoita sei maererano nehutano hwehutano?