High Purity Pharma API CAS14769-73-4 Hydrochloride Levamisole Base
Wickr/Teregiramu: Daisey521
Whatsapp : 008618034511316
Skype: live:.cid.93f1bd48473d87a8
Email: saleroom@yeah.net
Basic Information
Tsanangudzo
A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole ine S configuration.Inoshandiswa (kazhinji semunyu wemonohydrochloride) kurapa hutachiona hwegonye munguruve, hwai nemombe uye yaimboshandiswa muhuma s seadjuvant kune chemotherapy kurapwa kweakasiyana kenza.Inoshandiswawo zvakanyanya sechipombwe kune coccaine.
Zviratidzo
Levamisole (Ergamisol) is antiparasite drug yakawanikwa kuwedzera T-cell function uye cellular immune.Mushonga unovandudza kupona kwevarwere vane resected colorectal cancers painosanganiswa ne5-fluorouracil;nzira yekudyidzana iyi haizivikanwe.Levamisole haina antitumor inorwisa kenza yakasimbiswa kana metastatic uye haina kuwanikwa inobatsira mukurapa adjuvant yegomarara kunze kwegomarara remukati.
Mhedzisiro mikuru yelevamisole kusvotwa uye anorexia.Mapundu eganda, kuvaviwa, zviratidzo zvakaita sedzihwa, uye fivha zvakaonekwawo.
Zviratidzo
Levamisole (Ergamisol) yakatanga kugadzirwa semushonga unorwisa helminthic.Inowedzera zvinokurudzira zvinokonzerwa nemaantigen, mitogens, lymphokines, uye chemotactic zvinhu pa lymphocytes, granulocytes, uye macrophages.Yakaratidzwa kuwedzera T cell-mediated immunity.
Levamisole yakashandiswa zvinobudirira mukurapa zvirwere zvisingaperi.Iyo zvakare yakatenderwa kuti ishandiswe pamwe chete nefluorouracil mukurapa colorectal cancer.
Usage
Uses Biological response modifier.
Uses Levamisole inoshandiswa kune yekutanga uye yechipiri immunodeficient mamiriro, autoimmune zvirwere, zvisingaperi uye reoccurring zvirwere, huru intestine adenocarcinoma, helmintosis, uye rheumatoid arthritis.Mazwi akafanana emushonga uyu anoti decaris, tetramizole, nemamwe.
Levimasole zvakare mushonga wesarudzo weacardiasis.Ongororo dzakawanda dzinoratidza kuti dhizi rimwe chete relevamisole rinoporesa kubva ku90 kusvika ku100% yevarwere vane ascardiasis, kunyanya avo vane A. duodenale.Haina kunyanya kushanda pakurwisa ancylostomiasis uye strongyloidiasis.Zvisinei, haisi kushanda paN. americanus.Zvinoita sezvingangoita kuti ine gangliostimulating mhedzisiro pamaparasite tishu munzvimbo dzese dzeparasympathetic uye dzinonzwira tsitsi.Uyezve, zvinofungidzirwa kuti mushonga uyu une immunomodulatory mhedzisiro pane inotambira zvisikwa.Mazwi akafanana emushonga uyu anoti decaris, solacil, ergamisol, tramisol, immunol, nevamwe.
Clinical Kushandisa
Ascariasis Hookworm chirwere
Levamisole yakashandiswa mu rheumatoid arthritis uye mamwe mamiriro anonzi anopindura kune ayo immunomodulatory basa.
Therapeutic Basa
Antiinflammatory
Antimicrobial basa
Chiitiko chayo chikuru chinopesana neAsc.lumbricoides uye hookworms.Honye dzakaoma mitezo uye dzinopfuudzwa mutsvina mukati memaawa mashomanene.
Pharmaceutical Applications
Iyo l-isomer ye tetramisole, inowanikwa se monohydrochloride.Iyo d-isomer haina anthelmintic chiitiko.Inonyungudika mumvura uye inogadzikana munzvimbo yakaoma.
Nzira yekuita
Levamisole ine immunomodulating chiitiko.Zvinotendwa kuti inogadzirisa masero emagetsi ekudzivirira muviri, uye nzira yekuita kwayo inogona kusanganiswa nekushanda uye kuwedzera kukura kweT-lymphocytes, kuwedzera kwenhamba ye monocytes uye kushandiswa kwe macrophages, uyewo nekuwedzera kwekuita uye hemotaxis ye neutrophylic. granulocytes.Levamisole inoratidzawo chiito che anthelmint.Iyo inowedzerawo muviri wese resistivity uye inodzoreredza yakashandurwa T-lymphocyte uye phagocyte basa.Inogona zvakare kuzadzisa immunomodulatory basa nekusimbisa iyo isina kusimba maitiro emasero ekudzivirira, kunetesa kuita kwakasimba, uye kusave nemhedzisiro pane yakajairika maitiro.