Gutera umunwa Anabolic Steroid L-Triiodothyronine T3 Ifu ya Anabolic Steroide Ifu CasNO.55-06-1
T3 (Sodium ya Liothytonine) Ibisobanuro byihuse
- L-Triiodothyronine (T3)
- Alias: 3,3 ', 5-Triiodo-L-thyroninesodiumsalt, Sodium (2S) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propanoate
- Isuku: 99%
- Umubare w'iyandikisha rya CAS: 55-06-1
- Einecs No: 200-223-5
- MF: C15H11I3NNaO4
- MW: 672.96
- Kugaragara: ifu yera cyangwa yoroheje yumuhondo, hafi uburyohe.
- Icyiciro: Icyiciro cya farumasi
- Ububiko: Igicucu, kubungabunga kugarukira
- Imikoreshereze: Ifata inzira hafi ya zose zifata umubiri, harimo gukura no gutera imbere, metabolisme, ubushyuhe bwumubiri, hamwe n umuvuduko wumutima, nko kuvura indwara zo kwiheba no gukoresha nk'inyongera yibinure.
- T3 (Sodium ya Liothytonine)Gusaba
- Ifata hafi ya buri kintu cyose cyimikorere yumubiri, harimo gukura no gutera imbere, metabolisme, ubushyuhe bwumubiri, hamwe n umuvuduko wumutima.T3 byongera umuvuduko wibanze wa metabolike, bityo, byongera ogisijeni yumubiri hamwe nogukoresha ingufu.Igipimo fatizo cya metabolike nigipimo gito cya caloric gisabwa kugirango ubuzima bukomeze umuntu kuruhuka.T3 ikora mubice byinshi byumubiri biri mumubiri, usibye bike harimo ururenda na testis.Yongera umusaruro wa Na + / K + -ATPase kandi, muri rusange, yongera ibicuruzwa bya macromolecules ya endogenous itandukanye yongerera synthesis no gutesha agaciro.
T3 (Liothytonine Sodium) Ibisobanuro
Triiodothyronine, izwi kandi nka T3, ni imisemburo ya tiroyide.Ifata hafi ya buri kintu cyose cyimiterere yumubiri, harimo gukura no gukura, metabolisme, ubushyuhe bwumubiri, n umuvuduko wumutima.
Umusaruro wa T3 hamwe na prohormone thyroxine (T4) ukorwa na hormone itera tiroyide (TSH), isohoka muri glande ya pitoito.Iyi nzira igengwa nuburyo bwo gufunga ibitekerezo: Kwiyongera kwa T3, na T4 muri plasma yamaraso bibuza umusaruro wa TSH muri glande ya pitoito.Mugihe imyunvire yiyi misemburo igabanuka, glande ya pitoito yongera umusaruro wa TSH, kandi muribwo buryo, hashyizweho uburyo bwo kugenzura ibitekerezo kugirango bigabanye ingano ya hormone ya tiroyide iri mumaraso.
Nka misemburo nyayo, ingaruka za T3 kumitsi zigenewe zikubye hafi inshuro enye ugereranije na T4.Mu misemburo ya tiroyide ikorwa, hafi 20% ni T3, naho 80% ikorwa nka T4.Hafi ya 85% ya T3 izenguruka nyuma ikorwa muri tiroyide ikuraho atome ya iyode muri atome ya karubone nimero ya gatanu yimpeta yo hanze ya T4.Ibyo ari byo byose, kwibumbira hamwe kwa T3 muri plasma yamaraso yumuntu ni kimwe cya mirongo ine na T4.Ibi bigaragarira mubyukuri kubera igice gito cyubuzima bwa T3, ni iminsi 2.5 gusa. Ibi ugereranije nubuzima bwa kimwe cya kabiri cya T4, ni iminsi 6.5.
COA:
Ingingo | Ibisobanuro | Igisubizo | |
Kugaragara | Ifu idafite impumuro nziza, hafi yera cyangwa ifu yamabara | pass | |
Gukemura | 1, Gushonga cyane mumazi | pass | |
2, gushonga gato muri alcool | pass | ||
3, muburyo budashobora gukemuka mubindi byinshi byumuti | pass | ||
4, ikuraho ibisubizo byamazi ya sodium hydroxide yumuti | Pass | ||
Kumenyekanisha | a) Shyushya mg hafi 50 hamwe nigitonyanga gito cya acide sulfurike muri farufari ikomeye: imyuka ya violet ya iyode ihindagurika. | pass | |
b) Igihe cyo kugumana impinga nini cyemezwa kuri RS | pass | ||
Gutakaza Kuma | Ntabwo arenze 4.0% | 0.46% | |
[a] 20 / D. C = 1 muri 1M HCl / EtOH 1: 4 | +18 ~ + 22o | + 20.9o | |
Suzuma (HPLC) | Ntabwo ari munsi ya 95.0% | 99.18% | |
Sodium ya Levothyroxine | Ntabwo arenze 5.0% | 0,68% | |
Umwanzuro: | Kugeza kuri Standard yohereza hanze |