Nafarelin CAS: 76932-56-4 RS-94991-298 Nasanyl

Nafarelin, igurishwa mu mazina yubucuruzi nka Synarel, ni gonadotropine irekura imisemburo agonist (GnRH agonist) ikoreshwa mu kuvura endometriose nubugimbi bwangavu.Ikoreshwa kandi mu kuvura fibroide yo muri nyababyeyi, kugenzura intanga ngore mu gihe cyo gusama kwa vitro (IVF), no mu rwego rwo kuvura imisemburo ihuza ibitsina.Umuti ukoreshwa nka spray yizuru inshuro ebyiri cyangwa eshatu kumunsi.

Ingaruka mbi za nafarelin zifitanye isano no kubura imisemburo ya hormone kandi ikubiyemo ibimenyetso byerekana urugero rwa testosterone nkeya hamwe na estrogene nkeya, nka flash ashyushye, imikorere mibi yimibonano mpuzabitsina, atrophyie ibyara, na osteoporose.Nafarelin ni gonadotropine irekura imisemburo agonist (GnRH agonist) ikora mukurinda gonado gukora imisemburo yimibonano mpuzabitsina.Irashobora kugabanya imisemburo yimibonano mpuzabitsina mubitsina byombi 95%.Nafarelin ni peptide ni analogue ya GnRH.

Nafarelin yatangijwe gukoreshwa mu buvuzi mu 1990. Ikoreshwa cyane ku isi, harimo Amerika y'Amajyaruguru, Uburayi, ndetse no mu bindi bice by'isi.Uyu muti nimwe mubintu bibiri gusa byakoreshejwe mubuvuzi GnRH iboneka nka spray yizuru, ikindi ni Bucherelin

Gukoresha ubuvuzi:
Nafarelin yemerewe kuvura endometriose n'ubwangavu.Ikoreshwa kandi mu kuvura fibroide nyababyeyi.Umuti ukoreshwa mukurwanya intanga ngore mugihe cyo gusama vitro (IVF).Nafarelin ikoreshwa nkumubyigano wubwangavu bwurubyiruko no guhagarika urugero rwa testosterone kubagore bahindura ibitsina.Nafarelin irashobora kandi gukoreshwa mu kuvura hypertrichose na syndrome ya polycystic ovary igabanya urugero rwa gonadotropine na androgene.Nibyiza mukuvura hyperplasia nziza