Myomoduline CAS: 110570-93-9 H-Pro-Met-Ser-Met-Leu-Arg-Leu-NH2

Neuropeptide myoduline, umutima muto ukora peptide (SCP) na proteine ​​ya buccal ikwirakwizwa cyane muri phylum mollusca kandi ifite imirimo ikomeye ya physiologiya.Hano turasobanura ikwirakwizwa rirambuye rya buri cyiciro cya peptide muri sisitemu yo hagati yo hagati (CNS) ya Lymnaea stagnalis dukoresheje tekinike ya immunocytochemic hamwe no kurangi irangi rya neuron ryerekanwe na electrophysiology.Turatanga raporo kubyerekeranye no kwigunga no kuranga imiterere ya Lymnaomoduline PMSMLRLamide, isa na myomoduline A kuva murukwavu.Ubudahangarwa bwa Myomoduline buherereye muri ganglia zose uko ari 11, ingirangingo zazo, hamwe n'imitsi ya peripheri.Mubihe byinshi, immunoreactivite ya myomoduline igaragara mumatsinda ya neuron yerekana peptide ya FMRFamide, ariko no mubindi byinshi bya neuron.Double labeling assay yerekanye ubudahangarwa bwa myomoduline muri visceral yera interneurons igira uruhare mumikorere yumutima.Scp imeze nkubudahangarwa bw'umubiri nayo igaragara muri ganglia yose, kandi ibimenyetso bibiri byerekana ibimenyetso byerekana ko bifitanye isano na cluster yihariye ya exons zitandukanye zitandukanye zitandukanye muri CNS ya gene ya FMRFamide ahantu henshi.Nyamara, ibiranga antiserum ebyiri za SCP zikoreshwa muri ubu bushakashatsi byerekana ko zikorana na FMRFamide na n-terminal yaguye ya peptide ya FmrFamide.Guhitamo preadsorption ukoresheje peptide yambukiranya imipaka byatumye habaho kurandura irangi ryinshi no kugumana ubudahangarwa bw'umubiri bwa SCP gusa muri buccal na foot ganglia.Buccal protein immunoreactivite yagarukiraga kuri buccal na foot ganglia.Ntabwo bihuye no gukwirakwiza myomoduline cyangwa SCP.Ibice byinshi byo gukingira indwara biboneka muri ganglion.Ntabwo bihuye no gukwirakwiza myomoduline cyangwa SCP.Ibice byinshi byo gukingira indwara biboneka muri ganglion.Ntabwo bihuye no gukwirakwiza myomoduline cyangwa SCP.Ibice byinshi byo gukingira indwara biboneka muri ganglion.