Gutanga ibicuruzwa 99% Byera Ifu Yera Antitumor Polypeptide Pharma Grade Kanseri Ubushakashatsi MELITTIN CAS 20449-79-0

MELITTIN CAS 20449-79-0 Ikoreshwa:

Melitin nicyo kintu cyingenzi kigize ubumara bwinzuki.Beevenom ni ubwoko bwubumara bubonerana bufite impumuro nziza ihumura glande yubumara bwinzuki hamwe na glande.Iyo irenze, isohoka muri stinger.Mubice byinshi bigize ubumara bwinzuki, melittin ifite ibintu byinshi, bingana na 50% byuburemere bwumye bwubumara bwinzuki, kandi bufite ibikorwa byibinyabuzima byinshi.Melittin ni peptide y'umurongo igizwe na aside amine 26, ifite uburemere bugereranije bwa 2849. Melittin ifite ibikorwa biologiya byinshi.Ubushakashatsi bugezweho bwa farumasi bwerekanye ko bufite anti-inflammatory, analgesic, ibuza gukusanya platine, kurwanya SIDA nizindi ngaruka nyinshi.Melittin irashobora gutanga ingaruka zikomeye zo kwica ku ngirabuzimafatizo zitandukanye binyuze mu buryo butandukanye, kandi ni imiti isanzwe irwanya ibibyimba.

Melittin irashobora kubuza gukura no kororoka kwubwoko burenga 20 bwa Gram-positif na bagiteri mbi, kandi irashobora kandi kongera imbaraga za antibacterial effet ya sulfonamide na penisiline.Melittin yangiza ingirabuzimafatizo ya bagiteri ihuza na membrane kugirango igere ku ntego ya bacteriolysis.Melittin n'ibiyikomokaho bitandatu birashobora guhindura imikorere ya lymphocytes T yanduye virusi itera sida, bikabuza kwandura virusi itera sida, kandi bikagabanya kwandura virusi.

1. Ingaruka zo kwica mu buryo butaziguye Mu bushakashatsi bwa vitro bwemeje ko melittin igira ingaruka zigaragara zo kwica ku mirongo itandukanye ya kanseri y'ibibyimba nka osteosarcoma, kanseri y'intanga ngore, na glioma, kandi ingaruka zo kwica zifitanye isano neza na dose.Melittin irashobora kwica uturemangingo twibibyimba kandi ikabuza gukura kwingirabuzimafatizo, kandi nta ngaruka zigaragara zigira ku mikurire ya selile zisanzwe.Melittin irashobora kwinjiza muri selile ya selile ya K562, igakora imyenge, igatera Ca2 + kwinjira, ikongera ubukana bwa Ca2 + mu ngirabuzimafatizo, igatera lysis, kandi ikica selile K562.Muri rusange abantu bemeza ko melittin ishonga mitochondrial membrane selile, ikabuza imikorere isanzwe yubuhumekero ya selile yibibyimba, ikangiza ubushobozi bwubuhumekero bwa aerobic, ikabuza imikurire yumubiri wibibyimba, kandi ikica selile yibibyimba.
2. Ingaruka zo gukingira indwara Ubudahangarwa bw'akagari ni ikintu cy'ingenzi kirinda umubiri ibibyimba n'indwara ziterwa na virusi.Imiterere yumubiri wumubiri wumubiri ufite uruhare runini muguhinduka no gukura kw'ibibyimba.Kongera imikorere yumubiri wa selile birashobora kugira ingaruka zimwe zo kurwanya ibibyimba.
3. Kwinjiza kanseri y'ibibyimba apoptose Apoptose, izwi kandi ku rupfu rwa porogaramu, ni inzira y'ibinyabuzima ikora igenzurwa na genes zitandukanye.Kubwibyo, apoptose ninzira ikora, ikubiyemo gukora, imvugo no kugenzura urukurikirane rwa gen.Ubushakashatsi bugezweho bwerekanye ko imiti myinshi ya chimiotherapeutique ishobora kugera ku ntego zo kuvura itera apoptose mu ngirabuzimafatizo za kanseri.Niba gutera apoptose byabaye kimwe mubipimo byo gusuzuma imiti igabanya ubukana.

Melittin irashobora guhagarika ibikorwa bya sPLA2 biva ahantu hatandukanye, kandi igipimo cyo kubuza ibikorwa bya sPLA2 mumazi ya synovial fluid abarwayi ba RA gishobora kugera kuri 96%.Kubwibyo, gukoresha melittin birashobora kugabanya iterambere rya RA.

Sub-dose melittin irashobora kugabanya cyane igipimo cya lysis yo kuzuza selile.Ubu buryo bwo gukingira bushobora kuba bufitanye isano na melittin iteza Ca2 + kwinjira, itera sisitemu yo gukwirakwiza ibimenyetso byo mu nda hamwe na poroteyine ikingira.Birasabwa ko ikoreshwa rya melittin ikwiye rifite agaciro kanini kivura RA hamwe na Chemicalbook.Mu myaka yashize, ubushakashatsi bwerekanye ko kwibumbira hamwe kwa melittin bishobora kugira ingaruka kumikorere ya selile binyuze mumiyoboro itandukanye kandi bigira ingaruka zitandukanye mubinyabuzima.Gukoresha neza melittin bizatanga imiti mishya yindwara zimwe.