Isuku ryinshi Pharma API CAS14769-73-4 Hydrochloride Levamisole Base
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Amakuru Yibanze
Ibisobanuro
A 6-fenyl-2,3,5,6-tetrahydroimidazo [2,1-b] [1,3] thiazole ifite iboneza S.Irakoreshwa (muri rusange nk'umunyu wa monohydrochloride) mu kuvura indwara zanduza parasitike mu ngurube, intama n'inka kandi yahoze ikoreshwa muri huma s nk'inyongera ya chimiotherapie yo kuvura kanseri zitandukanye.Irakoreshwa kandi cyane nk'umusambanyi wa coccaine.
Ibyerekana
Levamisole (Ergamisol) ni imiti igabanya ubukana yabonetse kugirango yongere imikorere ya T-selile hamwe n’ubudahangarwa bw'umubiri.Uyu muti utezimbere ubuzima bw'abarwayi barwaye kanseri yibara iyo ihujwe na 5-fluorouracil;uburyo bw'imikoranire ntabwo buzwi.Levamisole ntabwo ifite ibikorwa byo kurwanya kanseri yanduye cyangwa metastatike kandi ntabwo yasanze ari ingirakamaro mu kuvura kanseri itandukanye na kanseri yibara.
Ingaruka mbi mbi za levamisole ni isesemi na anorexia.Kurwara uruhu, guhinda, ibimenyetso bya flulike, hamwe na feri nabyo byagaragaye.
Ibyerekana
Levamisole (Ergamisol) yabanje gukorwa nk'imiti igabanya ubukana.Itera imbaraga zo gukangura antigene, mitogene, lymphokines, hamwe na chimotactique kuri lymphocytes, granulocytes, na macrophage.Byerekanwe ko byongera ubudahangarwa bwa T selile.
Levamisole yakoreshejwe neza mu kuvura indwara zidakira.Byemejwe kandi gukoreshwa bifatanije na fluorouracil mu kuvura kanseri yibara.
Ikoreshwa
Gukoresha Guhindura ibisubizo byibinyabuzima.
Gukoresha Levamisole ikoreshwa muburyo bwambere nubwa kabiri bwikingira, indwara ziterwa na autoimmune, indwara zidakira kandi zisubiramo, amara manini adenocarcinoma, helmintose, na rubagimpande ya rubagimpande.Synonyme yibi biyobyabwenge ni decaris, tetramizole, nibindi.
Levimasole kandi nibiyobyabwenge byo guhitamo asikardiyasi.Iperereza ryinshi ryerekana ko ikinini kimwe cya levamisole gikiza kuva 90 kugeza 100% byabarwayi barwaye asikardiyasi, cyane cyane abanduye A. duodenale.Ntabwo ikora neza kurwanya ancylostomiasis na strongyloidiasis.Ariko, ntabwo ari byiza kurwanya N. amerika.Birasa nkaho bigira ingaruka za gangliostimulation ku ngingo za parasite haba mu turere twa parasimpatique n’impuhwe.Byongeye kandi, hafatwa ko uyu muti ugira ingaruka zo gukingira ibinyabuzima byakira.Synonyme yibi biyobyabwenge ni decaris, solacil, ergamisol, tramisol, immunol, nibindi.
Gukoresha Ivuriro
Indwara ya Ascariasis Hookworm
Levamisole yakoreshejwe muri rubagimpande ya rubagimpande nibindi bintu bimwe na bimwe bivugwa ko isubiza ibikorwa byayo byo gukingira indwara.
Imikorere yo kuvura
Kurwanya indwara
Igikorwa cya mikorobe
Igikorwa cyacyo nyamukuru kirwanya Asc.lumbricoides na hookworms.Inzoka ziramugaye kandi zanduzwa mumyanda mumasaha make.
Imiti ya farumasi
L-isomer ya tetramisole, iboneka nka monohydrochloride.D-isomer ntigikorwa cya anthelmintic.Irashobora gushonga cyane mumazi kandi irahagaze neza.
Uburyo bwibikorwa
Levamisole ifite ibikorwa byo gukingira indwara.Byizerwa ko igenga imikorere ya selile yubudahangarwa bw'umubiri, kandi uburyo bwibikorwa byayo birashobora kuba bifitanye isano no gukora no gukura kwa T-lymphocytes, kwiyongera kwa monocytes no gukora macrophage, ndetse no kongera ibikorwa na hemotaxis ya neutrophylic granulocytes.Levamisole yerekana kandi ibikorwa bya anthelmint.Yongera kandi imbaraga zo kurwanya umubiri muri rusange kandi igarura imikorere ya T-lymphocyte na fagocyte.Irashobora kandi gusohoza imikorere yubudahangarwa ikomeza imbaraga nke zubudahangarwa bwimikorere ya selile, kugabanya imbaraga zikomeye, kandi nta ngaruka bigira mubisanzwe.