page_banner

ibicuruzwa

Exendin-4 CAS 141758-74-9 Exenatide Acetate Umunyu Exenatide

ibisobanuro bigufi:


  • Izina rusange:Exendin-4
  • CAS No.:141758-74-9
  • Inzira ya molekulari:C184H282N50O60S
  • Uburemere bwa molekile:4186.57188
  • Ipaki:Icupa, Umufuka, Ikarito, Ingoma
  • Igihe cyo gutanga:Iminsi 3 nyuma yo kubona ubwishyu
  • Express:DHL, UPS, FedEx, Amaposita nibindi. (Zab: irashobora gukurikiza ibyo abakiriya bakeneye)
  • Uburyo bwo kwishyura:Kohereza banki, Bitcoin, Western Union nibindi
  • Whatsapp:008619832408762
  • Wickr:fairyqf
  • Imeri: salesperson66@yeah.net
  • Ibicuruzwa birambuye

    Ibicuruzwa

    Menyesha:

    Email : salesperson66@yeah.net

    whatsapp: +8619832408762

    wickr: umugani

    Skype: +8619832408762

     

    Ibiranga:

    Izina rusange Exenatide Izina ry'icyongereza Exenatide umunyu wa acetate
    Numero ya CAS 141758-74-9
    Inzira ya molekulari C184H282N50O60S
    Uburemere bwa molekile 4186.57000
    Misa nyayo 4184.03000
    PSA 1775.05000
    Imiterere yo kubika Ikidodo, ubike kuri -20ºC
    Igihagararo Nta kubora, nta reaction izwi izwi iyo ikoreshejwe kandi ibitswe ukurikije ibisobanuro

     

    Ikoreshwa:

    Exenatide niwo muti wa mbere mu cyiciro gishya cy’abarwanya diyabete uzwi ku izina rya incretin mimetics, kandi ugaragazwa nkubuvuzi bufatika bwo kunoza uburyo bwo kurwanya indwara ya glycemic ku barwayi barwaye diyabete yo mu bwoko bwa 2 bafata metformine, sulfonylurea, cyangwa byombi, ariko ntibabifite yageze ku kugenzura bihagije glycemic.Exenatide nigereranya ryimikorere ya incretin yumuntu Glucagon-Nka Peptide-1 (GLP-1).GLP-1 isanzwe irekurwa mu ngirabuzimafatizo zo mu gice cya GI mu rwego rwo gusubiza ibiryo kandi ikora kuri reseptor yayo kuri b-selile kugirango insuline ikure glucose.Exenatide ni agoniste ikora igihe kirekire kuri reseptor ya GLP-1.Ni verisiyo yubukorikori ya peptide ya 39-amino acide iboneka mumasemburo ya macandwe ya Gila monster lizard.kandi kandi igabanya urugero rwinshi rwa serum glucagon mugihe cya hyperglycemic ikurikira ifunguro, ariko ntirubangamira irekurwa rya glucagon mugusubiza hypoglycemia.Uburyo bwo gufata imiti ya exenatide ni mg 5 cyangwa 10 mg kabiri kumunsi, itangwa nkinshinge zo mu nda mugihe cyisaha imwe mbere yo kurya mugitondo na nimugoroba.Nyuma yubuyobozi bwubutaka, impuzandengo ya plasma ya exenatide igera kuri 2.1 h, kandi umwirondoro wa plasma pharmacokinetic ni dose ugereranije.Ibintu bibi bikunze kugaragara byavuzwe na exenatide harimo isesemi, kuruka, impiswi, kumva urwenya, umutwe, kubabara umutwe, na dyspepsia.

    Exendin-4 irashobora gukora GLP-1 reseptor, reseptor irashobora kongera urugero rwa cAMP ya selile pancreatic acinar selile mumyanya ndangagitsina, ariko nta ngaruka igira kuri reseptor ya VIP.

    Exendin-4 yakoreshejwe nka mimetics ya incretin yo kuvura mu ngirabuzimafatizo za HepG2 kugirango hirindwe ingaruka z'ibikoresho bifasha.Byakoreshejwe kandi nka r (GLP-1R) agonist kugirango wirinde kwivanga mubintu bifasha.

    证书

    包装


  • Mbere:
  • Ibikurikira:

  • Andika ubutumwa bwawe hano hanyuma utwohereze