Ubushinwa Igurisha Bishyushye CAS 623172-56-5 Palmitoyl Tripeptide-5

Kurwanya gusaza

Syn-Coll, cyangwa palmitoyl tripeptide-3/5 (Palmitoyl-lysyl-valyl-lysine bistrifluoracetate umunyu), ni ikimenyetso cyogukora oligopeptide yerekanwe muguteza imbere kolagen haba muri vitro ndetse no mubushakashatsi bwa vivo binyuze mubintu bikura TGFβ.Uburyo bwiyi peptide busa nibikorwa bya trombosponin I (TSPI).TSPI igaragarira mu ngirabuzimafatizo, cyane cyane mugihe cyo gukira ibikomere.Iyi poroteyine ihuza TGFβ yihishe kandi itera impinduka zifatika, byongera umusaruro wa kolagen nkingaruka zo hasi.Ubushakashatsi bumwe bwerekanye ko kuvura ibikomere bya TSPI null na peptide KRFK byashoboye gutabara ibikorwa bya TSP1 biterwa na TGFβ muri selile dermal.Syn-Coll ni inkomoko yuru ruhererekane rwahujwe na acide ya acide kugirango yongere kwinjira.Muri selile dermal fibroblast, ingaruka za farumasi ya peptide ifitanye isano, KFK, ni ukongera synthesis ya kolagen no kugabanya imvugo ya MMP-1 binyuze muri TGFβ.Ikigeragezo cyagenzuwe ku bakorerabushake 60 cyerekanye ko Syn-Coll yagabanije ububobere bwuruhu rwiza kuruta amavuta ya platbo na Pal-KTTKS, iyo akoreshejwe kabiri kumunsi iminsi 84.

Ibisobanuro

Palmitoyl tripeptide-5 ni peptide ikora kandi igizwe n'iminyururu 3 ya aside amine ihuza hamwe na aside irike.Palmitoyl tripeptide irashobora kwinjira muri epidermis kandi irashobora kwinjira cyane muri dermis, aho ishobora gufasha kubyutsa umusaruro wa kolagen kandi igafasha gukura neza kwimitsi.

Ibisobanuro

Palmitoyl tripeptide-5 ni peptide yo mu kirere.

Gukoresha

Palmitoyl Tripeptide-5 igizwe n'iminyururu ya aside amine kandi irashobora kwinjira muri epidermis ikinjira cyane muri dermisi, aho ishobora gufasha mu kongera umusaruro wa kolagen no gukura kw'imitsi myiza.

Gukoresha Palmitoyl Tripeptide-5 ni igice cyo kwanduza selile, kandi iteza imbere umusaruro wa kolagen.Bikunze gukoreshwa muburyo bwo kwisiga no kurwanya amavuta yo kwisiga.

inyungu

Palmitoyl Tripeptide-5 ni gusana cyane peptide nyinshi, kunoza neza isura yuruhu bitewe no gusaza kuva defenseto ikora ya selile epidermis, hasi ya membrane na corium layer, egstretch, ibimenyetso bya acne na scar bitewe na laser, nibindi. kumara igihe kirekire atin-gusaza.Ibicuruzwa bya Winkeypatent mu Bushinwa.Bisabwa dosiye ni 1 ~ 5%.

Uburyo bwibikorwa

Palmitoyl tripeptide-5 ikora ku byakira uruhu rwihariye kandi igatera umusaruro wa kolagen mu ngirabuzimafatizo zacu.Ihindura uruhu rwacu, igabanya isura yiminkanyari n'imirongo myiza.Bituma uruhu rwawe rusa neza kandi rushya.Palmitoyl Tripeptide-5 nayo ikorana na aside hyaluronic na sisitemu yo gukora elastine.Ingaruka ya kombine yongerewe amazi, kugabanya inkari zuruhu no kongera uruhu.