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Kurwanya gusaza Hexapeptide-11 CAS 161258-30-6 Mugabanye isura yiminkanyari

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  • Izina rusange:Hexapeptide-11
  • CAS No.:161258-30-6
  • Inzira ya molekulari:C36H48N6O7
  • Uburemere bwa molekile:676.8
  • Ipaki:Icupa, Umufuka, Ikarito, Ingoma
  • Igihe cyo gutanga:Iminsi 3 nyuma yo kubona ubwishyu
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    Ibiranga:

    Izina rusange Hexapeptide-11 Izina ry'icyongereza Hexapeptide-11
    Numero ya CAS 161258-30-6
    Inzira ya molekulari C.36H.48N.6O.7
    Uburemere bwa molekile 676.80200
    Misa nyayo 676.35800
    PSA 201.71000
    LogP 4.09300

     

    Ikoreshwa:

    Hexapeptide-11 numu moderi mushya wumuyoboro wa proteostasis muri fibroblast ya diploid yumuntu.

    Hexapeptide-11 igabanya isura y'imirongo myiza n'iminkanyari, ibi bikaba byiyongera cyane muburyo bwose bwo kwita ku ruhu n'ibicuruzwa birwanya gusaza.Ifite aside idasanzwe ya aside amine ifasha gukoresha urugero rwa kolagen no kongera imbaraga mu ruhu.

    Kumenyekanisha fibroblast kuri Hexapeptide-11 byateje imbere urugero no gukora biterwa na proteasome, autophagy, chaperone hamwe na antioxydeant ibisubizo bijyanye na gen.Byongeye kandi, byateje imbere kwiyongera kwa kirimbuzi ya Nrf2;urwego rwo hejuru rwerekana proteasomal protein subunits no kongera ibikorwa bya proteasome peptidase.Dukurikije ibyo twabonye twabonye ko Hexapeptide-11 yarinze cyane fibroblast kwirinda okiside-stress-yunganiwe na selile senescence itaragera, mu gihe muri vivo ivugurura ry’uruhu mu ngingo z’abantu ryateje imbere uruhu rworoshye.

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